Huei-Ling Chiu1, Pi-Tuan Chan2, Hsin Chu3,4,5, Shu-Tai Sheen Hsiao6, Doresses Liu7, Chueh-Ho Lin8,9, Kuei-Ru Chou1,10,11. 1. School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan. 2. Department of Nursing, En Chu Kong Hospital, Taipei, Taiwan. 3. Aviation Physiology Research Laboratory, Gangshan Branch, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan. 4. Institute of Aerospace and Undersea Medicine, School of Medicine, Taipei, Taiwan. 5. Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. 6. Department of Nursing, Taipei Medical University Hospital, Taipei, Taiwan. 7. Department of Nursing, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. 8. School of Gerontology Health Management, College of Nursing, Taipei Medical University, Taipei, Taiwan. 9. Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan. 10. Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan. 11. Department of Nursing, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.
Abstract
OBJECTIVES: To explore the effects of light therapy on behavioral disturbances (BDs), sleep quality, and depression. DESIGN: Meta-analysis of randomized controlled trials. SETTING: PubMed, Cochrane Library, Medline, EMBASE, Web of Science, and clinicaltrials.gov of selected randomized controlled trials and previous systematic reviews were searched. PARTICIPANTS: Cognitively impaired persons. MEASUREMENTS: Information was extracted on study characteristics, quality assessment, and outcomes. Outcome measures included BDs, sleep quality, and depression. RESULTS: Nine randomized controlled trials were examined. The results showed that light therapy has a moderate effect on BD (g = -0.61) and depression (g = -0.58) and a small effect on total sleep time at night (g = 0.25). Subgroup analysis indicated that a light intensity of 2,500 lux or greater has a greater effect on depression than an intensity of less than 2,500 lux (P = .03), and the low risk of bias in blinding was superior to the RCTs deemed to be of high or unclear risk of bias in blinding in terms of BD (P = .02). CONCLUSION: Light therapy can relieve BD, improve sleep quality, and alleviate symptoms of depression for cognitively impaired persons.
OBJECTIVES: To explore the effects of light therapy on behavioral disturbances (BDs), sleep quality, and depression. DESIGN: Meta-analysis of randomized controlled trials. SETTING: PubMed, Cochrane Library, Medline, EMBASE, Web of Science, and clinicaltrials.gov of selected randomized controlled trials and previous systematic reviews were searched. PARTICIPANTS: Cognitively impaired persons. MEASUREMENTS: Information was extracted on study characteristics, quality assessment, and outcomes. Outcome measures included BDs, sleep quality, and depression. RESULTS: Nine randomized controlled trials were examined. The results showed that light therapy has a moderate effect on BD (g = -0.61) and depression (g = -0.58) and a small effect on total sleep time at night (g = 0.25). Subgroup analysis indicated that a light intensity of 2,500 lux or greater has a greater effect on depression than an intensity of less than 2,500 lux (P = .03), and the low risk of bias in blinding was superior to the RCTs deemed to be of high or unclear risk of bias in blinding in terms of BD (P = .02). CONCLUSION: Light therapy can relieve BD, improve sleep quality, and alleviate symptoms of depression for cognitively impaired persons.
Authors: Mariana Alvina Dos Santos; Ana Paula da Conceição; Renata Eloah de Lucena Ferretti-Rebustini; Marcia Aparecida Ciol; Margareth McLean Heithkemper; Diná de Almeida Lopes Monteiro da Cruz Journal: Rev Lat Am Enfermagem Date: 2018-11-14