Nikolaos K Kanakaris1,2,3, Tess Greven4,5, Robert M West6, Arie B Van Vugt7, Peter V Giannoudis4,8. 1. Clinical Lead Major Trauma Centre, Academic Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK. n.kanakaris@nhs.net. 2. Academic Department of Trauma and Orthopaedics, Leeds General Infirmary, Clarendon Wing, Level A, Leeds, West Yorkshire, LS13EX, UK. n.kanakaris@nhs.net. 3. Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, Leeds, UK. n.kanakaris@nhs.net. 4. Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, Leeds, UK. 5. Medisch Spectrum Twente, Enschede, The Netherlands. 6. Department of Biostatistics, University of Leeds, Leeds, UK. 7. Department of Trauma Surgery, Medisch Spectrum Twente, Enschede, The Netherlands. 8. NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK.
Abstract
PURPOSE: The incidence of low energy pelvic fractures (FPFs) in the elderly is increasing. Comorbidities, decreased bone-quality, problematic fracture fixation and poor compliance represent some of their specific difficulties. In the absence of uniform management, a standard operating procedure (SOP) was introduced to our unit, aiming to improve the quality of services provided to these patients. METHODS: A cohort study was contacted to test the impact of (1) using a specific clinical algorithm and (2) using different antiosteoporotic drugs. Multivariate regression analysis was used to determine prognostic factors. Study endpoints were the time-to-healing, length-of-stay, return to pre-injury mobility, union status, mortality and complications. RESULTS: A total of 132 elderly patients (≥65 years) admitted during the period 2012-2014 with FPFs were enrolled. High-energy fractures, acetabular fractures, associated trauma affecting mobility, pathological pelvic lesions and operated FPFs were used as exclusion criteria. The majority of included patients were females (108/132; 81.8%), and the mean age was 85.8 years (range 67-108). Use of antiosteoporotics was associated with a shorter time of healing (p = 0.036). Patients treated according to the algorithm showed a significant protection against malunion (p < 0.001). Also, adherence to the algorithm allowed more patients to return to their pre-injury mobility status (p = 0.039). CONCLUSIONS: The use of antiosteoporotic medication in elderly patients with fragility pelvic fractures was associated with faster healing, whilst the adherence to a structured clinical pathway led to less malunions and non-unions and return to pre-injury mobility state.
PURPOSE: The incidence of low energy pelvic fractures (FPFs) in the elderly is increasing. Comorbidities, decreased bone-quality, problematic fracture fixation and poor compliance represent some of their specific difficulties. In the absence of uniform management, a standard operating procedure (SOP) was introduced to our unit, aiming to improve the quality of services provided to these patients. METHODS: A cohort study was contacted to test the impact of (1) using a specific clinical algorithm and (2) using different antiosteoporotic drugs. Multivariate regression analysis was used to determine prognostic factors. Study endpoints were the time-to-healing, length-of-stay, return to pre-injury mobility, union status, mortality and complications. RESULTS: A total of 132 elderly patients (≥65 years) admitted during the period 2012-2014 with FPFs were enrolled. High-energy fractures, acetabular fractures, associated trauma affecting mobility, pathological pelvic lesions and operated FPFs were used as exclusion criteria. The majority of included patients were females (108/132; 81.8%), and the mean age was 85.8 years (range 67-108). Use of antiosteoporotics was associated with a shorter time of healing (p = 0.036). Patients treated according to the algorithm showed a significant protection against malunion (p < 0.001). Also, adherence to the algorithm allowed more patients to return to their pre-injury mobility status (p = 0.039). CONCLUSIONS: The use of antiosteoporotic medication in elderly patients with fragility pelvic fractures was associated with faster healing, whilst the adherence to a structured clinical pathway led to less malunions and non-unions and return to pre-injury mobility state.
Entities:
Keywords:
Elderly; Fragility fractures; Osteoporosis; Pelvic fracture; Standard operating procedure
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