Literature DB >> 2873254

High molecular weight microtubule-associated proteins: purification by electro-elution and amino acid compositions.

K S Kosik, S F Bakalis, D J Selkoe, M W Pierce, L K Duffy.   

Abstract

The high molecular weight microtubule-associated proteins (MAPs) consist of MAPs 1A, 1B, 1C, 2A, and 2B. The proteins have been prepared from rat brain by using taxol and resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The individual proteins were purified by electro-elution from stained fixed gels and shown to migrate at their original mobility without proteolysis. Amino acid compositions of purified MAP 1 and 2 component proteins are reported and compared.

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Year:  1986        PMID: 2873254     DOI: 10.1002/jnr.490150411

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN: 0360-4012            Impact factor:   4.164


  3 in total

Review 1.  Genetics of Alzheimer disease.

Authors:  Lynn M Bekris; Chang-En Yu; Thomas D Bird; Debby W Tsuang
Journal:  J Geriatr Psychiatry Neurol       Date:  2010-12       Impact factor: 2.680

Review 2.  Tau function and dysfunction in neurons: its role in neurodegenerative disorders.

Authors:  Jesús Avila; Filip Lim; Francisco Moreno; Carlos Belmonte; A Claudio Cuello
Journal:  Mol Neurobiol       Date:  2002-06       Impact factor: 5.590

3.  Characterization by atomic force microscopy of Alzheimer paired helical filaments under physiological conditions.

Authors:  F Moreno-Herrero; M Pérez; A M Baró; J Avila
Journal:  Biophys J       Date:  2004-01       Impact factor: 4.033

  3 in total

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