Literature DB >> 28731482

Radiofluorination of a NHC-PF5 adduct: toward new probes for 18F PET imaging.

Boris Vabre1, Kantapat Chansaenpak2, Mengzhe Wang3, Hui Wang3, Zibo Li3, François P Gabbaï1.   

Abstract

The radiofluorination of N-heterocyclic carbene (NHC) phosphorus(v) fluoride adducts has been investigated. The results show that the IMe-PF5 derivative (IMe = 1,3-dimethylimidazol-2-ylidene) undergoes a Lewis acid promoted 18F-19F isotopic exchange. The resulting radiofluorinated probe is remarkably resistant to hydrolysis both in vitro as well as in vivo.

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Year:  2017        PMID： 28731482      PMCID： PMC5615223          DOI： 10.1039/c7cc04402j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  27 in total

1.  Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.

Authors:  Ulrich auf dem Keller; Caroline L Bellac; Ying Li; Yuanmei Lou; Philipp F Lange; Richard Ting; Curtis Harwig; Reinhild Kappelhoff; Shoukat Dedhar; Michael J Adam; Thomas J Ruth; François Bénard; David M Perrin; Christopher M Overall
Journal:  Cancer Res       Date:  2010-08-20       Impact factor: 12.701

2.  18F-labeling of peptides by means of an organosilicon-based fluoride acceptor.

Authors:  Ralf Schirrmacher; Gerrit Bradtmöller; Esther Schirrmacher; Oliver Thews; Julia Tillmanns; Thomas Siessmeier; Hans G Buchholz; Peter Bartenstein; Björn Wängler; Christof M Niemeyer; Klaus Jurkschat
Journal:  Angew Chem Int Ed Engl       Date:  2006-09-11       Impact factor: 15.336

Review 3.  Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography.

Authors:  Philip W Miller; Nicholas J Long; Ramon Vilar; Antony D Gee
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  Dual mode fluorescent (18)F-PET tracers: efficient modular synthesis of rhodamine-[cRGD]2-[(18)F]-organotrifluoroborate, rapid, and high yielding one-step (18)F-labeling at high specific activity, and correlated in vivo PET imaging and ex vivo fluorescence.

Authors:  Zhibo Liu; Mark Alex Radtke; May Q Wong; Kuo-Shyan Lin; Donald T Yapp; David M Perrin
Journal:  Bioconjug Chem       Date:  2014-09-29       Impact factor: 4.774

5.  Stoichiometric leverage: rapid 18F-aryltrifluoroborate radiosynthesis at high specific activity for click conjugation.

Authors:  Zhibo Liu; Ying Li; Jerome Lozada; Paul Schaffer; Michael J Adam; Thomas J Ruth; David M Perrin
Journal:  Angew Chem Int Ed Engl       Date:  2013-01-11       Impact factor: 15.336

6.  Lewis acidity of organofluorophosphonium salts: hydrodefluorination by a saturated acceptor.

Authors:  Christopher B Caputo; Lindsay J Hounjet; Roman Dobrovetsky; Douglas W Stephan
Journal:  Science       Date:  2013-09-20       Impact factor: 47.728

7.  A novel method of 18F radiolabeling for PET.

Authors:  William J McBride; Robert M Sharkey; Habibe Karacay; Christopher A D'Souza; Edmund A Rossi; Peter Laverman; Chien-Hsing Chang; Otto C Boerman; David M Goldenberg
Journal:  J Nucl Med       Date:  2009-05-14       Impact factor: 10.057

8.  Synthesis of p-(di-tert-butyl[(18)F]fluorosilyl)benzaldehyde ([(18)F]SiFA-A) with high specific activity by isotopic exchange: a convenient labeling synthon for the (18)F-labeling of N-amino-oxy derivatized peptides.

Authors:  Esther Schirrmacher; Björn Wängler; Marek Cypryk; Gerrit Bradtmöller; Martin Schäfer; Michael Eisenhut; Klaus Jurkschat; Ralf Schirrmacher
Journal:  Bioconjug Chem       Date:  2007-11-21       Impact factor: 4.774

Review 9.  From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging.

Authors:  Vadim Bernard-Gauthier; Justin J Bailey; Zhibo Liu; Björn Wängler; Carmen Wängler; Klaus Jurkschat; David M Perrin; Ralf Schirrmacher
Journal:  Bioconjug Chem       Date:  2015-11-25       Impact factor: 4.774

10.  [(18)F]-Group 13 fluoride derivatives as radiotracers for positron emission tomography.

Authors:  Kantapat Chansaenpak; Boris Vabre; François P Gabbaï
Journal:  Chem Soc Rev       Date:  2015-11-09       Impact factor: 54.564
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  1 in total

1.  Coumarin Probe for Selective Detection of Fluoride Ions in Aqueous Solution and Its Bioimaging in Live Cells.

Authors:  Kantapat Chansaenpak; Anyanee Kamkaew; Oratai Weeranantanapan; Khomson Suttisintong; Gamolwan Tumcharern
Journal:  Sensors (Basel)       Date:  2018-06-26       Impact factor: 3.576
  1 in total

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