A Martorell1, E Alonso2, L Echeverría3, C Escudero4, R García-Rodríguez5, C Blasco6, J Bone7, J Borja-Segade5, T Bracamonte3, A Claver8, J L Corzo9, B De la Hoz10, R Del Olmo11, O Dominguez12, V Fuentes-Aparicio13, I Guallar7, H Larramona14, F Martín-Muñoz15, V Matheu16, A Michavila17, I Ojeda18, P Ojeda18, M Piquer12, P Poza16, M Reche19, P Rodríguez Del Río4, M Rodríguez20, F Ruano21, S Sánchez-García4, S Terrados22, L Valdesoiro, M Vazquez-Ortiz23. 1. Department of Allergology, University General Hospital, Valencia, Valencia, Spain. 2. Department of Pediatric Allergy, Gregorio Marañón Hospital, Madrid, Spain. 3. Department of Pediatric Allergy, Severo Ochoa University Hospital, Leganés, Spain. 4. Department of Pediatric Allergy, Niño Jesús University Children's Hospital, Madrid, Spain. 5. Department of Allergology, University General Hospital, Ciudad Real, Spain. 6. Department of Pediatric Allergy, Vall d'Hebron Hospital, Barcelona, Spain. 7. Department of Pediatric Allergy, Miguel Servet University Hospital, Zaragoza, Spain. 8. Quirón Dexeus University Hospital, Barcelona, Spain. 9. Department of Pediatric Allergy, Carlos Haya University Hospital, Málaga, Spain. 10. Department of Allergology, Ramón y Cajal Hospital, Madrid, Spain. 11. Department of Pediatric Allergy, University Hospital, Móstoles, Spain. 12. Department of Pediatric Allergy, San Joan de Deu Hospital, Barcelona, Spain. 13. Department of Allergology, San Carlos Clinic Hospital, Madrid, Spain. 14. Department of Pediatric Allergy, Parc Taulí University Hospital, Sabadell, Spain. 15. Department of Allergology, La Paz Children's Hospital, Madrid, Spain. 16. Allergology Unit-North Chest Hospital, Santa Cruz de Tenerife, Spain. 17. Department of Pediatric Allergy, General Hospital, Castellón, Spain. 18. Ojeda Clinic, Madrid, Spain. 19. Department of Allergology, Infanta Sofía Hospital, San Sebastián de los Reyes, Spain. 20. Department of Allergology, Alcorcón Foundation Hospital, Alcorcón, Spain. 21. Department of Allergy, Infanta Leonor Hospital, Madrid, Spain. 22. Department of Pediatric Allergy, Ramón y Cajal Hospital, Madrid, Spain. 23. Pediatric Allergy, Department of Medicine, Imperial College London, United Kingdom.
Abstract
BACKGROUND AND OBJECTIVE: Cow milk and egg are the most frequent causes of food allergy in the first years of life. Oral immunotherapy (OIT) has been investigated as an alternative to avoidance diets. No clinical practice guidelines on the management of OIT with milk and egg are currently available. Objectives: To develop clinical guidelines for OIT based on available scientific evidence and the opinions of experts. METHODS: A review was made of studies published between 1984 and June 2016, doctoral theses published in Spain, summaries of communications at scientific meetings (SEAIC, SEICAP, EAACI, and AAAAI), and the consensus of opinion established by a group of experts from the scientific societies SEICAP and SEAIC. RESULTS: Recommendations were established regarding the indications, requirements and practical aspects of the different phases of OIT, as well as special protocols for patients at high risk of adverse reactions. CONCLUSIONS: Clinical practice guidelines based on the consensus reached between Spanish experts are presented for the management of OIT with milk and egg.
BACKGROUND AND OBJECTIVE:Cowmilk and egg are the most frequent causes of food allergy in the first years of life. Oral immunotherapy (OIT) has been investigated as an alternative to avoidance diets. No clinical practice guidelines on the management of OIT with milk and egg are currently available. Objectives: To develop clinical guidelines for OIT based on available scientific evidence and the opinions of experts. METHODS: A review was made of studies published between 1984 and June 2016, doctoral theses published in Spain, summaries of communications at scientific meetings (SEAIC, SEICAP, EAACI, and AAAAI), and the consensus of opinion established by a group of experts from the scientific societies SEICAP and SEAIC. RESULTS: Recommendations were established regarding the indications, requirements and practical aspects of the different phases of OIT, as well as special protocols for patients at high risk of adverse reactions. CONCLUSIONS: Clinical practice guidelines based on the consensus reached between Spanish experts are presented for the management of OIT with milk and egg.
Authors: Jan L Brozek; Ramon T Firmino; Antonio Bognanni; Stefania Arasi; Ignacio Ansotegui; Amal H Assa'ad; Sami L Bahna; Roberto Berni Canani; Martin Bozzola; Derek K Chu; Lamia Dahdah; Christophe Dupont; Piotr Dziechciarz; Motohiro Ebisawa; Elena Galli; Andrea Horvath; Rose Kamenwa; Gideon Lack; Haiqi Li; Alberto Martelli; Anna Nowak-Węgrzyn; Nikolaos G Papadopoulos; Ruby Pawankar; Yetiani Roldan; Maria Said; Mario Sánchez-Borges; Raanan Shamir; Jonathan M Spergel; Hania Szajewska; Luigi Terracciano; Yvan Vandenplas; Carina Venter; Siw Waffenschmidt; Susan Waserman; Amena Warner; Gary W K Wong; Alessandro Fiocchi; Holger J Schünemann Journal: World Allergy Organ J Date: 2022-04-23 Impact factor: 5.516
Authors: P Bégin; E S Chan; H Kim; M Wagner; M S Cellier; C Favron-Godbout; E M Abrams; M Ben-Shoshan; S B Cameron; S Carr; D Fischer; A Haynes; S Kapur; M N Primeau; J Upton; T K Vander Leek; M M Goetghebeur Journal: Allergy Asthma Clin Immunol Date: 2020-03-18 Impact factor: 3.406