Literature DB >> 28731031

NLRP9b: a novel RNA-sensing inflammasome complex.

Chinh Ngo1, Si Ming Man1.   

Abstract

Inflammasome sensors recognize pathogens and danger signals and assemble an immune signaling complex, which induces the secretion of pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis. A new study published in Nature now describes a new inflammasome sensor NLRP9b in intestinal epithelial cells, which in concert with the RNA sensor DHX9, recognize short dsRNA from Rotavirus.

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Year:  2017        PMID： 28731031      PMCID： PMC5674164          DOI： 10.1038/cr.2017.93

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  9 in total

Review 1.  Converging roles of caspases in inflammasome activation, cell death and innate immunity.

Authors:  Si Ming Man; Thirumala-Devi Kanneganti
Journal:  Nat Rev Immunol       Date:  2015-12-14       Impact factor: 53.106

2.  DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.

Authors:  Tuğçe Aktaş; İbrahim Avşar Ilık; Daniel Maticzka; Vivek Bhardwaj; Cecilia Pessoa Rodrigues; Gerhard Mittler; Thomas Manke; Rolf Backofen; Asifa Akhtar
Journal:  Nature       Date:  2017-03-29       Impact factor: 49.962

Review 3.  2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis.

Authors:  Jacqueline E Tate; Anthony H Burton; Cynthia Boschi-Pinto; A Duncan Steele; Jazmin Duque; Umesh D Parashar
Journal:  Lancet Infect Dis       Date:  2011-10-24       Impact factor: 25.071

4.  Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Authors:  Si Ming Man; Lee J Hopkins; Eileen Nugent; Susan Cox; Ivo M Glück; Panagiotis Tourlomousis; John A Wright; Pietro Cicuta; Tom P Monie; Clare E Bryant
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-06       Impact factor: 11.205

Review 5.  Discovery of rotavirus: Implications for child health.

Authors:  Ruth Bishop
Journal:  J Gastroenterol Hepatol       Date:  2009-10       Impact factor: 4.029

6.  The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.

Authors:  Fabio Martinon; Kimberly Burns; Jürg Tschopp
Journal:  Mol Cell       Date:  2002-08       Impact factor: 17.970

7.  Nlrp6 regulates intestinal antiviral innate immunity.

Authors:  Penghua Wang; Shu Zhu; Long Yang; Shuang Cui; Wen Pan; Ruaidhri Jackson; Yunjiang Zheng; Anthony Rongvaux; Qiangming Sun; Guang Yang; Shandian Gao; Rongtuan Lin; Fuping You; Richard Flavell; Erol Fikrig
Journal:  Science       Date:  2015-10-22       Impact factor: 47.728

8.  Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Authors:  Shu Zhu; Siyuan Ding; Penghua Wang; Zheng Wei; Wen Pan; Noah W Palm; Yi Yang; Hua Yu; Hua-Bing Li; Geng Wang; Xuqiu Lei; Marcel R de Zoete; Jun Zhao; Yunjiang Zheng; Haiwei Chen; Yujiao Zhao; Kellie A Jurado; Ningguo Feng; Liang Shan; Yuval Kluger; Jun Lu; Clara Abraham; Erol Fikrig; Harry B Greenberg; Richard A Flavell
Journal:  Nature       Date:  2017-06-21       Impact factor: 49.962

9.  NLRP9B protein is dispensable for oocyte maturation and early embryonic development in the mouse.

Authors:  Hui Peng; Xiujiao Lin; Fang Liu; Cheng Wang; Wenchang Zhang
Journal:  J Reprod Dev       Date:  2015-09-28       Impact factor: 2.214
  9 in total
  3 in total

Review 1.  Treading a HOSTile path: Mapping the dynamic landscape of host cell-rotavirus interactions to explore novel host-directed curative dimensions.

Authors:  Upayan Patra; Urbi Mukhopadhyay; Arpita Mukherjee; Shanta Dutta; Mamta Chawla-Sarkar
Journal:  Virulence       Date:  2021-12       Impact factor: 5.882

Review 2.  NLRP9 in innate immunity and inflammation.

Authors:  Breanne Mullins; Jueqi Chen
Journal:  Immunology       Date:  2020-12-20       Impact factor: 7.397

Review 3.  Inflammasome-targeting natural compounds in inflammatory bowel disease: Mechanisms and therapeutic potential.

Authors:  Qiuyun Xu; Weichen Sun; Jie Zhang; Youmin Mei; Jingyin Bao; Shengping Hou; Xiaorong Zhou; Liming Mao
Journal:  Front Immunol       Date:  2022-08-24       Impact factor: 8.786
  3 in total

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