Literature DB >> 2872846

Blood-brain barrier: interface between internal medicine and the brain.

W M Pardridge, W H Oldendorf, P Cancilla, H J Frank.   

Abstract

The blood-brain barrier separates brain interstitial space from blood and is formed by brain capillary endothelial cells that are fused together by epithelial-like tight junctions. Study of the blood-brain barrier traditionally has been a relatively arcane field, even for neurobiologists. However, advances over the last 10 years in understanding the transport physiology and cell biology of the brain capillary endothelial cell now provide insights into the pathogenesis of such problems as brain glucopenia, hepatic encephalopathy, therapeutic efficacy of alpha-methyldopa, brain edema in diabetic ketoacidosis, Alzheimer's disease, brain tumors, and lupus cerebritis.

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Year:  1986        PMID： 2872846     DOI： 10.7326/0003-4819-105-1-82

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  27 in total

Review 1.  Intrathecal chemotherapy with antineoplastic agents in children.

Authors:  A Ruggiero; V Conter; M Milani; E Biagi; I Lazzareschi; P Sparano; R Riccardi
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

2.  Morphological differentiation of endothelial cells co-cultured with astrocytes on type-I or type-IV collagen.

Authors:  M Tagami; K Yamagata; H Fujino; A Kubota; Y Nara; Y Yamori
Journal:  Cell Tissue Res       Date:  1992-05       Impact factor: 5.249

Review 3.  Blood-brain barrier and new approaches to brain drug delivery.

Authors:  W M Pardridge; R J Boado; K L Black; P A Cancilla
Journal:  West J Med       Date:  1992-03

4.  Sheaths of the spinal nerve roots. Permeability and structural characteristics of dorsal and ventral spinal nerve roots of the rat.

Authors:  C A Pettersson
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

Review 5.  Principles of pharmacotherapy: II. Pharmacokinetics.

Authors:  T J Pallasch
Journal:  Anesth Prog       Date:  1988 Jul-Aug

Review 6.  Drug transport across the blood-brain barrier.

Authors:  William M Pardridge
Journal:  J Cereb Blood Flow Metab       Date:  2012-08-29       Impact factor: 6.200

7.  Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study.

Authors:  T S Salahuddin; B B Johansson; H Kalimo; Y Olsson
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

8.  Blood supply of spinal nerve roots. An experimental study in the rat.

Authors:  C A Petterson; Y Olsson
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

9.  Concentrations of trimethoprim and sulfamethoxazole in cerebrospinal fluid and serum in mares with and without a dimethyl sulfoxide pretreatment.

Authors:  S L Green; I G Mayhew; M P Brown; R R Gronwall; G Montieth
Journal:  Can J Vet Res       Date:  1990-04       Impact factor: 1.310

10.  Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.

Authors:  A G Geiser; J J Letterio; A B Kulkarni; S Karlsson; A B Roberts; M B Sporn
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205
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