W W Wei1, X F Yang, H Gu, N P Liu. 1. Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Abstract
Objective: To determine the prevalence of diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN) in the Beijing Desheng Diabetic Eye Disease Study cohort and to investigate the association between DR and DPN. Methods: Cross-sectional study in a type 2 diabetic cohort. Questionnaires were collected and physical examinations were performed. Ophthalmologic examinations consisted of visual acuity with pinhole, slit-lamp examination of the anterior segment and seven-field 30(o) mydriatic fundus photography. The severity of DR was graded using a modified ETDRS method. Peripheral neuropathy examinations included 10-g Semmes-Weinstein monofilament, 128-Hz tuning fork and Tip-Therm. Statistical analysis was performed using SPSS software version 19.0. Results: A total of 959 patients with type 2 diabetes mellitus were enrolled, among whom 354 (36.9%) had DR and 523 (54.5%) had DPN. The prevalence of DPN was 61.8% in patients with DR and 50% in patients with no DR (χ(2)=13.66, P<0.01). Logistic regression analysis showed that DR was associated significantly with age (OR=1.03, 95%CI: 1.01-1.06) and gender (male) (OR=2.32, 95%CI: 1.51-3.58), whereas the presence of DPN increased the risk of DR (OR=1.5, 95%CI: 1.12-2.01). Conclusions: DPN is commonly seen in patients with type 2 diabetes mellitus and increases the risk of DR. (Chin J Ophthalmol, 2017, 53: 509-513).
Objective: To determine the prevalence of diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN) in the Beijing Desheng Diabetic Eye Disease Study cohort and to investigate the association between DR and DPN. Methods: Cross-sectional study in a type 2 diabetic cohort. Questionnaires were collected and physical examinations were performed. Ophthalmologic examinations consisted of visual acuity with pinhole, slit-lamp examination of the anterior segment and seven-field 30(o) mydriatic fundus photography. The severity of DR was graded using a modified ETDRS method. Peripheral neuropathy examinations included 10-g Semmes-Weinstein monofilament, 128-Hz tuning fork and Tip-Therm. Statistical analysis was performed using SPSS software version 19.0. Results: A total of 959 patients with type 2 diabetes mellitus were enrolled, among whom 354 (36.9%) had DR and 523 (54.5%) had DPN. The prevalence of DPN was 61.8% in patients with DR and 50% in patients with no DR (χ(2)=13.66, P<0.01). Logistic regression analysis showed that DR was associated significantly with age (OR=1.03, 95%CI: 1.01-1.06) and gender (male) (OR=2.32, 95%CI: 1.51-3.58), whereas the presence of DPN increased the risk of DR (OR=1.5, 95%CI: 1.12-2.01). Conclusions: DPN is commonly seen in patients with type 2 diabetes mellitus and increases the risk of DR. (Chin J Ophthalmol, 2017, 53: 509-513).