Literature DB >> 2872666

Acute sulphasalazine hepatotoxicity.

P E Jennings, R L Blandford, F D Rosenthal.   

Abstract

We describe a case of severe sulphasalazine hepatotoxicity. The features described are those of an acute hypersensitivity reaction which responded to drug withdrawal alone as steroids were withheld. Supportive treatment only is recommended for this potentially fatal condition.

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Year:  1986        PMID： 2872666      PMCID： PMC2418655          DOI： 10.1136/pgmj.62.726.305

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  5 in total

1.  Sulfonamide hepatic injury. Review of the literature and report of a case due to sulfamethoxazole.

Authors:  C A Dujovne; C H Chan; H J Zimmerman
Journal:  N Engl J Med       Date:  1967-10-12       Impact factor: 91.245

2.  Sulfasalazine toxic reactions. Hepatitis, fever, and skin rash with hypocomplementemia and immune complexes.

Authors:  A A Mihas; D J Goldenberg; R L Slaughter
Journal:  JAMA       Date:  1978-06-16       Impact factor: 56.272

3.  Hypersensitivity to salicylazosulfapyridine: renal and hepatic toxic reactions.

Authors:  A C Chester; L H Diamond; G E Schreiner
Journal:  Arch Intern Med       Date:  1978-07

4.  Sulphasalazine hepatotoxicity after 15 years' successful treatment for ulcerative colitis.

Authors:  T W Lennard; J R Farndon
Journal:  Br Med J (Clin Res Ed)       Date:  1983-07-09

5.  Sulfasalazine hepatotoxicity.

Authors:  J D Losek; S L Werlin
Journal:  Am J Dis Child       Date:  1981-11
  5 in total

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