Literature DB >> 28726105

Changes in levels of metabolic pathway gene expression under conditions of clear cell renal carcinoma.

V Yu Bashmakov1, T M Gorbacheva2, A V Panevina2, S A Solodskikh2, I P Moshurov3, A A Mikhaylov3, A Yu Maslov2, V N Popov2.   

Abstract

A whole-transcriptome analysis of gene expression in six samples of clear cell renal cancer was performed. Using bioinformatics methods, we established a relationship between gene expression data and changes in activity of metabolic pathways: in this cancer type, the expression of genes involved in the metabolism of carbohydrates, lipids, and amino acids as well as in energy metabolism changed most significantly.

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Year:  2017        PMID： 28726105     DOI： 10.1134/S1607672917030024

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  8 in total

Review 1.  Metabolic genes in cancer: their roles in tumor progression and clinical implications.

Authors:  Eiji Furuta; Hiroshi Okuda; Aya Kobayashi; Kounosuke Watabe
Journal:  Biochim Biophys Acta       Date:  2010-02-01

2.  HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.

Authors:  Jennifer S Isaacs; Yun Jin Jung; David R Mole; Sunmin Lee; Carlos Torres-Cabala; Yuen-Li Chung; Maria Merino; Jane Trepel; Berton Zbar; Jorge Toro; Peter J Ratcliffe; W Marston Linehan; Len Neckers
Journal:  Cancer Cell       Date:  2005-08       Impact factor: 31.743

3.  Obesity, hypertension, and the risk of kidney cancer in men.

Authors:  W H Chow; G Gridley; J F Fraumeni; B Järvholm
Journal:  N Engl J Med       Date:  2000-11-02       Impact factor: 91.245

Review 4.  Papillary renal cell carcinoma: A review of the current therapeutic landscape.

Authors:  Giulia Courthod; Marcello Tucci; Massimo Di Maio; Giorgio V Scagliotti
Journal:  Crit Rev Oncol Hematol       Date:  2015-05-27       Impact factor: 6.312

Review 5.  Links between metabolism and cancer.

Authors:  Chi V Dang
Journal:  Genes Dev       Date:  2012-05-01       Impact factor: 11.361

6.  Dietary fat and risk of renal cell carcinoma in the USA: a case-control study.

Authors:  Kaye E Brock; Gloria Gridley; Brian C-H Chiu; Abby G Ershow; Charles F Lynch; Kenneth P Cantor
Journal:  Br J Nutr       Date:  2008-09-12       Impact factor: 3.718

Review 7.  Genomic instability and cancer.

Authors:  George S Charames; Bharati Bapat
Journal:  Curr Mol Med       Date:  2003-11       Impact factor: 2.222

8.  Key pathways and genes controlling the development and progression of clear cell renal cell carcinoma (ccRCC) based on gene set enrichment analysis.

Authors:  Haipeng Huang; Yanyan Tang; Wenwu He; Qi Huang; Jianing Zhong; Zhanbin Yang
Journal:  Int Urol Nephrol       Date:  2013-08-14       Impact factor: 2.370
  8 in total

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