Literature DB >> 2872469

Radioimmunoassay of relaxin in pregnancy with an analogue of human relaxin.

L W Eddie, R J Bell, A Lester, M Geier, G Bennett, P D Johnston, H D Niall.   

Abstract

A radioimmunoassay for relaxin was developed in which a synthetic analogue of human relaxin was used as standard, tracer, and immunogen. Relaxin could not be measured in sera from men or non-pregnant women, but was measurable in pregnant women from the tenth week of gestation until term. Concentrations ranged from 0.19-1.18 ng/ml, with highest levels measured in the first trimester.

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Year:  1986        PMID: 2872469     DOI: 10.1016/s0140-6736(86)91662-4

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  6 in total

Review 1.  Maternal programming: Application of a developmental psychopathology perspective.

Authors:  Laura M Glynn; Mariann A Howland; Molly Fox
Journal:  Dev Psychopathol       Date:  2018-08

2.  Relaxin and gonadal steroid receptors in uterosacral ligaments of women with and without pelvic organ prolapse.

Authors:  Wolf Dietrich; Ksenia Elenskaia; Eva Obermayr; Reinhard Horvat; Klaus Mayerhofer; Wolfgang Umek; Robert Zeillinger; Engelbert Hanzal
Journal:  Int Urogynecol J       Date:  2011-11-29       Impact factor: 2.894

3.  Effects of recombinant H2 relaxin on the expression of matrix metalloproteinases and tissue inhibitor metalloproteinase in cultured early placental extravillous trophoblasts.

Authors:  Nobuyuki Maruo; Koji Nakabayashi; Senn Wakahashi; Ai Yata; Takeshi Maruo
Journal:  Endocrine       Date:  2008-01-31       Impact factor: 3.633

4.  Relaxin and beta-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss.

Authors:  Gihan Hashem; Qin Zhang; Takayuki Hayami; Jean Chen; Wei Wang; Sunil Kapila
Journal:  Arthritis Res Ther       Date:  2006       Impact factor: 5.156

5.  Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants.

Authors:  Tabassum Naqvi; Trang T Duong; Gihan Hashem; Momotoshi Shiga; Qin Zhang; Sunil Kapila
Journal:  Arthritis Res Ther       Date:  2004-10-29       Impact factor: 5.156

Review 6.  Relaxin as a natural agent for vascular health.

Authors:  Daniele Bani
Journal:  Vasc Health Risk Manag       Date:  2008
  6 in total

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