Literature DB >> 28723543

Necroptosis: (Last) Message in a Bubble.

Peter Vandenabeele1, Franck Riquet2, Benjamin Cappe3.   

Abstract

RIPK3 kinase-mediated phosphorylation of MLKL pseudokinase is the execution event of necroptosis. Two independent reports-in Immunity (Yoon et al., 2017) and Cell (Gong et al., 2017)-reveal that MLKL affects homeostatic membrane trafficking and necroptosis-enhanced bubble formation involving interaction with the ESCRT machinery.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28723543     DOI： 10.1016/j.immuni.2017.07.002

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  6 in total

1.  Biological events and molecular signaling following MLKL activation during necroptosis.

Authors:  Yi-Nan Gong; Cliff Guy; Jeremy Chase Crawford; Douglas R Green
Journal:  Cell Cycle       Date:  2017-08-30       Impact factor: 4.534

2.  MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis.

Authors:  Xiaoqin Wu; Kyle L Poulsen; Carlos Sanz-Garcia; Emily Huang; Megan R McMullen; Sanjoy Roychowdhury; Srinivasan Dasarathy; Laura E Nagy
Journal:  J Hepatol       Date:  2020-03-24       Impact factor: 25.083

3.  Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.

Authors:  Zikou Liu; Laura F Dagley; Kristy Shield-Artin; Samuel N Young; Aleksandra Bankovacki; Xiangyi Wang; Michelle Tang; Jason Howitt; Che A Stafford; Ueli Nachbur; Cheree Fitzgibbon; Sarah E Garnish; Andrew I Webb; David Komander; James M Murphy; Joanne M Hildebrand; John Silke
Journal:  EMBO J       Date:  2021-10-26       Impact factor: 11.598

4.  Vitamin C controls neuronal necroptosis under oxidative stress.

Authors:  Luciano Ferrada; María Jose Barahona; Katterine Salazar; Peter Vandenabeele; Francisco Nualart
Journal:  Redox Biol       Date:  2019-12-16       Impact factor: 11.799

5.  Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood.

Authors:  Anne K Voss; Andreas Strasser; Francine F S Ke; Kerstin Brinkmann
Journal:  Cell Death Dis       Date:  2022-04-07       Impact factor: 8.469

6.  Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.

Authors:  Lien Van Hoecke; Sandra Van Lint; Kenny Roose; Alexander Van Parys; Peter Vandenabeele; Johan Grooten; Jan Tavernier; Stefaan De Koker; Xavier Saelens
Journal:  Nat Commun       Date:  2018-08-24       Impact factor: 14.919
  6 in total

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