Literature DB >> 28723259

Inappropriate movement of Rac1 contributes to glucotoxicity of the islet β-cell.

Anjaneyulu Kowluru1.   

Abstract

Entities:  

Mesh：

Year:  2017        PMID： 28723259      PMCID： PMC5553397          DOI： 10.1080/15384101.2017.1345229

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


× No keyword cloud information.
  7 in total

1.  Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic β-Cells.

Authors:  Rajakrishnan Veluthakal; Daleep K Arora; Marc L Goalstone; Renu A Kowluru; Anjaneyulu Kowluru
Journal:  Cell Physiol Biochem       Date:  2016-11-02

2.  Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.

Authors:  Omar M Khan; Murali K Akula; Kristina Skålen; Christin Karlsson; Marcus Ståhlman; Stephen G Young; Jan Borén; Martin O Bergo
Journal:  Circulation       Date:  2013-01-18       Impact factor: 29.690

3.  Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors.

Authors:  Stephanie J Turner; Shunhui Zhuang; Tong Zhang; Gerry R Boss; Renate B Pilz
Journal:  Biochem Pharmacol       Date:  2007-09-01       Impact factor: 5.858

4.  Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification.

Authors:  Patrick J Roberts; Natalia Mitin; Patricia J Keller; Emily J Chenette; James P Madigan; Rachel O Currin; Adrienne D Cox; Oswald Wilson; Paul Kirschmeier; Channing J Der
Journal:  J Biol Chem       Date:  2008-07-09       Impact factor: 5.157

5.  Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells.

Authors:  Vaibhav Sidarala; Anjaneyulu Kowluru
Journal:  Apoptosis       Date:  2017-05       Impact factor: 4.677

Review 6.  Role of G-proteins in islet function in health and diabetes.

Authors:  Anjaneyulu Kowluru
Journal:  Diabetes Obes Metab       Date:  2017-09       Impact factor: 6.577

7.  Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.

Authors:  Y Zhu; P J Casey; A P Kumar; S Pervaiz
Journal:  Cell Death Dis       Date:  2013-04-04       Impact factor: 8.469
  7 in total
  5 in total

1.  [Effects of glycosylated hemoglobin and disease course on islet β-cell function in patients with type 2 diabetes].

Authors:  H E Yinhui; X U Haiyan; F U Qi; Yang Tao
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2019-09-30

Review 2.  Underappreciated roles for Rho GDP dissociation inhibitors (RhoGDIs) in cell function: Lessons learned from the pancreatic islet β-cell.

Authors:  Anjaneyulu Kowluru; Noah F Gleason
Journal:  Biochem Pharmacol       Date:  2021-12-28       Impact factor: 5.858

Review 3.  RACking up ceramide-induced islet β-cell dysfunction.

Authors:  Anjaneyulu Kowluru; Renu A Kowluru
Journal:  Biochem Pharmacol       Date:  2018-04-30       Impact factor: 5.858

4.  Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: reversal of such metabolic defects by metformin.

Authors:  Sartaj Baidwan; Anil Chekuri; DiAnna L Hynds; Anjaneyulu Kowluru
Journal:  Apoptosis       Date:  2017-11       Impact factor: 4.677

5.  The Dynamic Effects of Isosteviol on Insulin Secretion and Its Inability to Counteract the Impaired β-Cell Function during Gluco-, Lipo-, and Aminoacidotoxicity: Studies In Vitro.

Authors:  Wenqian Gu; Andreas Rebsdorf; Kjeld Hermansen; Søren Gregersen; Per Bendix Jeppesen
Journal:  Nutrients       Date:  2018-01-26       Impact factor: 5.717
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.