| Literature DB >> 2872297 |
F Ponzio, G Achilli, S Garattini, C Perego, G Sacchetti, S Algeri.
Abstract
3-Methoxytyramine formation was enhanced by amineptine (40 mg kg-1 i.p.) in the striatum and limbic area, indicating an increase in the concentration of dopamine in the extraneuronal space. Since dopamine turnover, determined as the rate of L-dopa accumulation, is reduced by the drug at short (10 min) times, the enhanced extraneuronal dopamine concentration seems mainly related to amineptine-induced inhibition of its uptake.Entities:
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Year: 1986 PMID： 2872297 DOI： 10.1111/j.2042-7158.1986.tb04572.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765