Literature DB >> 28722505

Lipolytic effect of compounds isolated from leaves of mulberry (Morus alba L.) in 3T3-L1 adipocytes.

Hong Xu Li1, Eunji Jo1, Chang-Seon Myung1, Young Ho Kim1, Seo Young Yang1.   

Abstract

In this study, 19 known compounds were isolated from mulberry (Morus alba L.) leaves. The lipid accumulation inhibitory activity of the isolated compounds was investigated. Compounds 4 and 12 showed good anti-adipogenic activity based on 3T3-L1 adipocytes with values of 36.6 ± 9.0 and 34.7 ± 4.0%, respectively. In addition, compounds 3, 6 and 15 showed significant inhibitory activity with values from 15.4 to 21.2% and compounds 2, 8-9 and 17-18 exhibited weak activity with values ranging from 2.1 to 10.7% at a concentration of 40.0 μM. These results show the potentiality that mulberry leaf is an excellent inhibitory phytochemical source against lipid accumulation.

Entities:  

Keywords:  Antiobesity; Lipid accumulation; Morus alba L.; Mulberry leaf

Mesh：

Substances：

Year:  2017        PMID： 28722505     DOI： 10.1080/14786419.2017.1354190

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  6 in total

1.  A Chemical Investigation of the Leaves of Morus alba L.

Authors:  Xiao-Yan Chen; Ting Zhang; Xin Wang; Mark T Hamann; Jie Kang; De-Quan Yu; Ruo-Yun Chen
Journal:  Molecules       Date:  2018-04-26       Impact factor: 4.411

2.  Mulberry leaf powder regulates antioxidative capacity and lipid metabolism in finishing pigs.

Authors:  Yingying Liu; Yinghui Li; Yi Xiao; Yinglin Peng; Jianhua He; Chen Chen; Dingfu Xiao; Yulong Yin; Fengna Li
Journal:  Anim Nutr       Date:  2020-12-18

Review 3.  The structure-activity relationship review of the main bioactive constituents of Morus genus plants.

Authors:  Jiejing Yan; Jingya Ruan; Peijian Huang; Fan Sun; Dandan Zheng; Yi Zhang; Tao Wang
Journal:  J Nat Med       Date:  2020-01-02       Impact factor: 3.192

4.  Identification of Bioactive Phytochemicals in Mulberries.

Authors:  Gilda D'Urso; Jurriaan J Mes; Paola Montoro; Robert D Hall; Ric C H de Vos
Journal:  Metabolites       Date:  2019-12-20

5.  Coumarin and Moracin Derivatives from Mulberry Leaves (Morus alba L.) with Soluble Epoxide Hydrolase Inhibitory Activity.

Authors:  Hong Xu Li; Myungsook Heo; Younghoon Go; Young Soo Kim; Young Ho Kim; Seo Young Yang; Wei Li
Journal:  Molecules       Date:  2020-08-31       Impact factor: 4.411

Review 6.  Morus alba L. Plant: Bioactive Compounds and Potential as a Functional Food Ingredient.

Authors:  Centhyea Chen; Umi Hartina Mohamad Razali; Fiffy Hanisdah Saikim; Azniza Mahyudin; Nor Qhairul Izzreen Mohd Noor
Journal:  Foods       Date:  2021-03-23
  6 in total

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