Literature DB >> 28722474

When will small molecule lactate dehydrogenase inhibitors realize their potential in the cancer clinic?

Reshma Rani1, Vinit Kumar2.   

Abstract

Entities:  

Keywords:  Warburg effect; cancer metabolism; drug discovery; hLDH5 inhibitors; tumor glycolysis

Mesh：

Substances：

Year:  2017        PMID： 28722474     DOI： 10.4155/fmc-2017-0082

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  3 in total

1.  Thiazole Derivatives as Inhibitors for the Treatment of Cancer Cells Resistant.

Authors:  Robert B Kargbo
Journal:  ACS Med Chem Lett       Date:  2018-02-21       Impact factor: 4.345

Review 2.  Natural products targeting human lactate dehydrogenases for cancer therapy: A mini review.

Authors:  Huankai Yao; Feng Yang; Yan Li
Journal:  Front Chem       Date:  2022-09-29       Impact factor: 5.545

3.  Targeting Lactate Dehydrogenase A with Catechin Resensitizes SNU620/5FU Gastric Cancer Cells to 5-Fluorouracil.

Authors:  Jung Ho Han; MinJeong Kim; Hyeon Jin Kim; Se Bok Jang; Sung-Jin Bae; In-Kyu Lee; Dongryeol Ryu; Ki-Tae Ha
Journal:  Int J Mol Sci       Date:  2021-05-20       Impact factor: 5.923
  3 in total

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