Literature DB >> 28721688

Morphine and the blood-brain barrier: diffusion, uptake, or efflux?

Karsten Bartels1, Konrad Meissner2.   

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Year:  2017        PMID： 28721688      PMCID： PMC6005186          DOI： 10.1007/s12630-017-0932-y

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN： 0832-610X            Impact factor:   5.063


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  18 in total

Review 1.  Astrocyte-endothelial interactions at the blood-brain barrier.

Authors:  N Joan Abbott; Lars Rönnbäck; Elisabeth Hansson
Journal:  Nat Rev Neurosci       Date:  2006-01       Impact factor: 34.870

2.  An observational study examining the effects of a surgically induced inflammatory response on the distribution of morphine and its metabolites into cerebrospinal fluid.

Authors:  Yan Wang; Kerry B Goralski; Derek J Roberts; Kathryn Landry; Mark E Issa; Lekha Sleno; Lisa C Julien; Jeremy Wood; Richard I Hall
Journal:  Can J Anaesth       Date:  2017-07-14       Impact factor: 5.063

Review 3.  Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy.

Authors:  David S Miller; Björn Bauer; Anika M S Hartz
Journal:  Pharmacol Rev       Date:  2008-06-17       Impact factor: 25.468

4.  Differential regulation of transport proteins in the periinfarct region following reversible middle cerebral artery occlusion in rats.

Authors:  P Dazert; Y Suofu; M Grube; A Popa-Wagner; H K Kroemer; G Jedlitschky; C Kessler
Journal:  Neuroscience       Date:  2006-09-25       Impact factor: 3.590

5.  Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration.

Authors:  Mladen V Tzvetkov; Joao N dos Santos Pereira; Ingolf Meineke; Ali R Saadatmand; Julia C Stingl; Jürgen Brockmöller
Journal:  Biochem Pharmacol       Date:  2013-07-05       Impact factor: 5.858

6.  Hydrophilic anti-migraine triptans are substrates for OATP1A2, a transporter expressed at human blood-brain barrier.

Authors:  Ziqiang Cheng; Houfu Liu; Na Yu; Fei Wang; Gang An; Yan Xu; Qian Liu; Chen-bing Guan; Andrew Ayrton
Journal:  Xenobiotica       Date:  2012-04-18       Impact factor: 1.908

7.  Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity.

Authors:  Heidrun Potschka; Maren Fedrowitz; Wolfgang Löscher
Journal:  J Pharmacol Exp Ther       Date:  2003-03-27       Impact factor: 4.030

8.  Increased drug delivery to the brain by P-glycoprotein inhibition.

Authors:  A J Sadeque; C Wandel; H He; S Shah; A J Wood
Journal:  Clin Pharmacol Ther       Date:  2000-09       Impact factor: 6.875

9.  Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study.

Authors:  Karsten Bartels; Qing Ma; Talaignair N Venkatraman; Christopher R Campos; Lindsay Smith; Ronald E Cannon; Mihai V Podgoreanu; Christopher D Lascola; David S Miller; Joseph P Mathew
Journal:  Heart Lung Circ       Date:  2014-05-23       Impact factor: 2.975

10.  P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Authors:  A H Schinkel; E Wagenaar; C A Mol; L van Deemter
Journal:  J Clin Invest       Date:  1996-06-01       Impact factor: 14.808
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