Literature DB >> 28721543

[Decision aids in complex polypharmacy : Medication data bases and counselling by clinical pharmacists].

W Weinrebe1, R Preda2, S Bischoff3, D Nussbickel2, M Humm2, K Jeckelmann4, S Goetz4.   

Abstract

The number of older people with polypharmacy (more than six drugs taken simultaneously) is increasing. The greatest proportion consists of guideline drugs, analgesics and psychopharmaceuticals because in many cases of geriatric multimorbidity several underlying main diseases are present which must be treated according to the guidelines. Polypharmacy is a complex and difficult situation for all treating physicians because substantial side effects and intoxication can be induced but it can also be very difficult to recognize which drug was at fault and how a reduction can be safely made. This article describes the exemplary case of a 77-year-old patient with drug-induced delirium and demonstrates the procedure followed. The question of rapid assistance by the utilization of medication data bases is described and the importance of clinical pharmacists is demonstrated. In the future working with medication data bases will possibly become increasingly more important for physicians and hopefully simpler. The case presented here also shows that the effective and justified reduction of drugs can show a very good effect and is possible.

Entities:  

Keywords:  Adverse drug reaction reporting systems; Delirium; Drug combinations; Drug-related side effects and adverse reactions; Multimorbidity

Mesh:

Year:  2017        PMID: 28721543     DOI: 10.1007/s00391-017-1285-4

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  14 in total

1.  Multimorbidity, polypharmacy and pharmacogenomics in old age.

Authors:  Jürgen Brockmöller; Julia C Stingl
Journal:  Pharmacogenomics       Date:  2017-03-14       Impact factor: 2.533

2.  Anticholinergic medication use and cognitive impairment in the older population: the medical research council cognitive function and ageing study.

Authors:  Chris Fox; Kathryn Richardson; Ian D Maidment; George M Savva; Fiona E Matthews; David Smithard; Simon Coulton; Cornelius Katona; Malaz A Boustani; Carol Brayne
Journal:  J Am Geriatr Soc       Date:  2011-06-24       Impact factor: 5.562

3.  Performance-oriented assessment of mobility problems in elderly patients.

Authors:  M E Tinetti
Journal:  J Am Geriatr Soc       Date:  1986-02       Impact factor: 5.562

4.  Clarifying confusion: the confusion assessment method. A new method for detection of delirium.

Authors:  S K Inouye; C H van Dyck; C A Alessi; S Balkin; A P Siegal; R I Horwitz
Journal:  Ann Intern Med       Date:  1990-12-15       Impact factor: 25.391

5.  Drug related medical emergencies in the elderly: role of adverse drug reactions and non-compliance.

Authors:  S Malhotra; R S Karan; P Pandhi; S Jain
Journal:  Postgrad Med J       Date:  2001-11       Impact factor: 2.401

6.  Hospitalizations because of adverse drug reactions in elderly patients admitted through the emergency department: a prospective survey.

Authors:  Pascale Olivier; Lionel Bertrand; Marie Tubery; Dominique Lauque; Jean-Louis Montastruc; Maryse Lapeyre-Mestre
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

Review 7.  Polypharmacy in elderly patients.

Authors:  Emily R Hajjar; Angela C Cafiero; Joseph T Hanlon
Journal:  Am J Geriatr Pharmacother       Date:  2007-12

8.  The timed "Up & Go": a test of basic functional mobility for frail elderly persons.

Authors:  D Podsiadlo; S Richardson
Journal:  J Am Geriatr Soc       Date:  1991-02       Impact factor: 5.562

Review 9.  Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review.

Authors:  Mohammed Saji Salahudeen; Stephen B Duffull; Prasad S Nishtala
Journal:  BMC Geriatr       Date:  2015-03-25       Impact factor: 3.921

10.  Number of medications and adverse drug events by unintentional poisoning among older adults in consideration of inappropriate drug use: a Swedish population-based matched case-control study.

Authors:  Christian Rausch; L Laflamme; U Bültmann; J Möller
Journal:  Eur J Clin Pharmacol       Date:  2017-03-09       Impact factor: 2.953

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