Kathleen Schenker1, Steven Blumer1, Diego Jaramillo2, Amanda L Treece3, Aashim Bhatia4. 1. Department of Radiology, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA. 2. Department of Radiology, Nicklaus Children's Hospital, Miami, FL, USA. 3. Departments of Pathology and Laboratory Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA. 4. Department of Radiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, 2200 Children's Way, Suite 1422, Nashville, TN, 37232, USA. Aashimbhatia@gmail.com.
Abstract
BACKGROUND: Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis. OBJECTIVE: To review three cases of epithelioid hemangioma of bone occurring in pediatric patients involving the epiphysis and to explore the imaging features of this tumor. MATERIALS AND METHODS: Retrospectively review three cases of epithelioid hemangioma occurring in skeletally immature patients. RESULTS: These tumors primarily involved the epiphyses or epiphyseal equivalent bones. One lesion was centered in the metaphysis but extended to the epiphysis. These are three cases presenting in an unusual location and at an unusual age. CONCLUSION: Epithelioid hemangioma, though rare, can occur in pediatric patients and appears to involve the epiphyses in these patients. This is in contrast to the usual age and location reported. Epithelioid hemangioma may be considered for an epiphyseal lesion in a skeletally immature patient.
BACKGROUND:Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis. OBJECTIVE: To review three cases of epithelioid hemangioma of bone occurring in pediatric patients involving the epiphysis and to explore the imaging features of this tumor. MATERIALS AND METHODS: Retrospectively review three cases of epithelioid hemangioma occurring in skeletally immature patients. RESULTS: These tumors primarily involved the epiphyses or epiphyseal equivalent bones. One lesion was centered in the metaphysis but extended to the epiphysis. These are three cases presenting in an unusual location and at an unusual age. CONCLUSION:Epithelioid hemangioma, though rare, can occur in pediatric patients and appears to involve the epiphyses in these patients. This is in contrast to the usual age and location reported. Epithelioid hemangioma may be considered for an epiphyseal lesion in a skeletally immature patient.
Entities:
Keywords:
Adolescent; Bone; Epiphysis; Epithelioid hemangioma; Magnetic resonance imaging; Radiography
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