Literature DB >> 28720933

Bioaccessibility of hydroxytyrosol and n-3 fatty acids as affected by the delivery system: simple, double and gelled double emulsions.

Susana Cofrades1, Ricard Bou1,2, Linda Flaiz1, Alba Garcimartín3, Juana Benedí3, Raquel Mateos1, Francisco J Sánchez-Muniz4, Raúl Olivero-David4, Francisco Jiménez-Colmenero1.   

Abstract

This study examines the influence of different food-grade n-3 PUFA-enriched simple emulsion (SE), double emulsion (DE) and gelled double emulsion (GDE) delivery systems on the extent of lipolysis, antioxidant capacity and the bioaccessibility of hydroxytyrosol (HTy). GDE emulsion offered better protection for HTy (89%) than the other systems (79% in SE and DE). The reducing capacity of the emulsions containing HTy were not altered during oral digestion. However, "in vitro" gastric and intestinal phases significantly reduced the antioxidant activity of all systems. The structural and physical state of GDE entailed a slowing-down of triacylglyceride hydrolysis (36.4%) in comparison with that of SE and DE (22.7 and 24.8% for SE and DE, respectively).

Entities:  

Keywords:  Antioxidant capacity; Emulsion-based delivery systems; Hydroxytyrosol; Lipolysis; n-3 fatty acids

Year:  2017        PMID: 28720933      PMCID: PMC5495701          DOI: 10.1007/s13197-017-2604-x

Source DB:  PubMed          Journal:  J Food Sci Technol        ISSN: 0022-1155            Impact factor:   2.701


  15 in total

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2.  One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development.

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3.  Preparation, characterization, and in vitro gastrointestinal digestibility of oil-in-water emulsion-agar gels.

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Journal:  Biosci Biotechnol Biochem       Date:  2013-03-07       Impact factor: 2.043

4.  Digestive stability of hydroxytyrosol, hydroxytyrosyl acetate and alkyl hydroxytyrosyl ethers.

Authors:  Gema Pereira-Caro; Beatriz Sarriá; Andrés Madrona; José Luis Espartero; María E Escuderos; Laura Bravo; Raquel Mateos
Journal:  Int J Food Sci Nutr       Date:  2012-01-24       Impact factor: 3.833

5.  Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay.

Authors:  R Pulido; L Bravo; F Saura-Calixto
Journal:  J Agric Food Chem       Date:  2000-08       Impact factor: 5.279

6.  Effect of thermally oxidized oil and fasting status on the short-term digestibility of ketolinoleic acids and total oxidized fatty acids in rats.

Authors:  Raul Olivero-David; Antonello Paduano; Vincenzo Fogliano; Paola Vitaglione; Sara Bastida; María José González-Muñoz; Juana Benedí; Raffaele Sacchi; Francisco José Sánchez-Muniz
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Review 7.  Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

Authors:  Christopher J H Porter; Natalie L Trevaskis; William N Charman
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Review 8.  Structured emulsion-based delivery systems: controlling the digestion and release of lipophilic food components.

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Journal:  Adv Colloid Interface Sci       Date:  2010-07-03       Impact factor: 12.984

9.  Hydroxytyrosol prevents oxidative deterioration in foodstuffs rich in fish lipids.

Authors:  Manuel Pazos; Ana Alonso; Isabel Sánchez; Isabel Medina
Journal:  J Agric Food Chem       Date:  2008-04-22       Impact factor: 5.279

10.  Preparation and impact of multiple (water-in-oil-in-water) emulsions in meat systems.

Authors:  S Cofrades; I Antoniou; M T Solas; A M Herrero; F Jiménez-Colmenero
Journal:  Food Chem       Date:  2013-03-07       Impact factor: 7.514

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  5 in total

1.  Gelled double emulsions as delivery systems for hydroxytyrosol and n-3 fatty acids in healthy pork patties.

Authors:  M Freire; S Cofrades; V Serrano-Casas; T Pintado; M J Jimenez; F Jimenez-Colmenero
Journal:  J Food Sci Technol       Date:  2017-09-14       Impact factor: 2.701

Review 2.  Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.

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Journal:  Nutrients       Date:  2017-09-26       Impact factor: 5.717

Review 3.  Progress in Colloid Delivery Systems for Protection and Delivery of Phenolic Bioactive Compounds: Two Study Cases-Hydroxytyrosol and Curcumin.

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4.  Effect of In Vitro Digestion on Water-in-Oil-in-Water Emulsions Containing Anthocyanins from Grape Skin Powder.

Authors:  Weili Xu; Yang Yang; Sophia Jun Xue; John Shi; Loong-Tak Lim; Charles Forney; Guihua Xu; Bio Sigui Bruno Bamba
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5.  Influence of gelation on the retention of purple cactus pear extract in microencapsulated double emulsions.

Authors:  Paz Robert; Cristina Vergara; Andrea Silva-Weiss; Fernando A Osorio; Rocío Santander; Carmen Sáenz; Begoña Giménez
Journal:  PLoS One       Date:  2020-01-16       Impact factor: 3.240

  5 in total

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