| Literature DB >> 28718427 |
Madeleine J Oudin1, Frank B Gertler2.
Abstract
MenaINV, an isoform of the motility regulator protein Mena, contributes to prometastatic phenotypes. Tumor microenvironment of metastasis (TMEM), a three-cell structure associated with intravasation, contains a stationary Mena-expressing tumor cell. TMEM density and MenaINV expression both correlate with poor clinical outcome in breast cancer patients. However, is MenaINV involved in TMEM assembly and function?Entities:
Keywords: Mena; biomarker; breast cancer; metastasis; tumor microenvironment of metastasis
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Year: 2016 PMID： 28718427 DOI： 10.1016/j.trecan.2016.11.004
Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025