Literature DB >> 28715244

Small Sample Methods for Multilevel Modeling: A Colloquial Elucidation of REML and the Kenward-Roger Correction.

Daniel McNeish1.   

Abstract

Studies on small sample properties of multilevel models have become increasingly prominent in the methodological literature in response to the frequency with which small sample data appear in empirical studies. Simulation results generally recommend that empirical researchers employ restricted maximum likelihood estimation (REML) with a Kenward-Roger correction with small samples in frequentist contexts to minimize small sample bias in estimation and to prevent inflation of Type-I error rates. However, simulation studies focus on recommendations for best practice, and there is little to no explanation of why traditional maximum likelihood (ML) breaks down with smaller samples, what differentiates REML from ML, or how the Kenward-Roger correction remedies lingering small sample issues. Due to the complexity of these methods, most extant descriptions are highly mathematical and are intended to prove that the methods improve small sample performance as intended. Thus, empirical researchers have documentation that these methods are advantageous but still lack resources to help understand what the methods actually do and why they are needed. This tutorial explains why ML falters with small samples, how REML circumvents some issues, and how Kenward-Roger works. We do so without equations or derivations to support more widespread understanding and use of these valuable methods.

Entities:  

Keywords:  Kenward-Roger; Restricted maximum likelihood; explanation; mixed model; tutorial

Mesh:

Year:  2017        PMID: 28715244     DOI: 10.1080/00273171.2017.1344538

Source DB:  PubMed          Journal:  Multivariate Behav Res        ISSN: 0027-3171            Impact factor:   5.923


  31 in total

1.  The Performance of Multivariate Methods for Two-Group Comparisons with Small Samples and Incomplete Data.

Authors:  Keenan A Pituch; Megha Joshi; Molly E Cain; Tiffany A Whittaker; Wanchen Chang; Ryoungsun Park; Graham J McDougall
Journal:  Multivariate Behav Res       Date:  2019-09-25       Impact factor: 5.923

2.  Enhanced gaze-following behavior in Deaf infants of Deaf parents.

Authors:  Rechele Brooks; Jenny L Singleton; Andrew N Meltzoff
Journal:  Dev Sci       Date:  2019-10-15

3.  Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis.

Authors:  Nishant Gupta; Hye-Seung Lee; Lisa R Young; Charlie Strange; Joel Moss; Lianne G Singer; Koh Nakata; Alan F Barker; Jeffrey T Chapman; Mark L Brantly; James M Stocks; Kevin K Brown; Joseph P Lynch; Hilary J Goldberg; Gregory P Downey; Angelo M Taveira-DaSilva; Jeffrey P Krischer; Kenneth Setchell; Bruce C Trapnell; Yoshikazu Inoue; Francis X McCormack
Journal:  Eur Respir J       Date:  2019-04-04       Impact factor: 16.671

4.  Auditory Detection Thresholds and Cochlear Resistivity Differ Between Pediatric Cochlear Implant Listeners With Enlarged Vestibular Aqueduct and Those With Connexin-26 Mutations.

Authors:  Kelly N Jahn; Molly D Bergan; Julie G Arenberg
Journal:  Am J Audiol       Date:  2020-01-14       Impact factor: 1.493

5.  Do therapist effects really impact estimates of within-patient mechanisms of change? A Monte Carlo simulation study.

Authors:  Fredrik Falkenström; Nili Solomonov; Julian A Rubel
Journal:  Psychother Res       Date:  2020-06-02

6.  Individual differences in parent and child average RSA and parent psychological distress influence parent-child RSA synchrony.

Authors:  Anna Fuchs; Erika Lunkenheimer; Frances Lobo
Journal:  Biol Psychol       Date:  2021-03-19       Impact factor: 3.251

7.  Pre-flight exercise and bone metabolism predict unloading-induced bone loss due to spaceflight.

Authors:  Leigh Gabel; Anna-Maria Liphardt; Paul A Hulme; Martina Heer; Sara R Zwart; Jean D Sibonga; Scott M Smith; Steven K Boyd
Journal:  Br J Sports Med       Date:  2021-02-17       Impact factor: 13.800

8.  Negative affect interference and fear of happiness are independently associated with depressive symptoms.

Authors:  D Gage Jordan; Amanda C Collins; Matthew G Dunaway; Jenna Kilgore; E Samuel Winer
Journal:  J Clin Psychol       Date:  2020-10-20

9.  Extending the I-squared statistic to describe treatment effect heterogeneity in cluster, multi-centre randomized trials and individual patient data meta-analysis.

Authors:  Karla Hemming; James P Hughes; Joanne E McKenzie; Andrew B Forbes
Journal:  Stat Methods Med Res       Date:  2020-09-21       Impact factor: 3.021

10.  A randomized controlled trial comparing non-steroidal anti-inflammatory and fusion protein inhibitors singly and in combination on the histopathology of bovine respiratory syncytial virus infection.

Authors:  Francisco R Carvallo Chaigneau; Paul Walsh; Maxim Lebedev; Victoria Mutua; Heather McEligot; Heejung Bang; Laurel J Gershwin
Journal:  PLoS One       Date:  2021-06-10       Impact factor: 3.240

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