Literature DB >> 28712823

An overview on biological functions and emerging therapeutic roles of apelin in diabetes mellitus.

Farzaneh Ghafarian Alipour1, Mohamad Reza Ashoori2, Younes Pilehvar-Soltanahmadi3, Nosratollah Zarghami4.   

Abstract

Type 2 diabetes mellitus is a common type of diabetes and considered as multifactorial disease. Apelin is an adipokine which secreted from white adipose tissue and involved in various functions such as insulin sensitivity and food intake. Many studies showed that apelin has a crucial role in diabetes and its concentration will change in relation with insulin resistance. In this review, we will discuss the roles of apelin in energy metabolism and pathogenesis of diabetes and explain why apelin can be a good candidate adipokine to promoting insulin sensitivity.
Copyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Apelin; Diabetes mellitus; Insulin resistance; Obesity

Mesh：

Substances：

Year:  2017        PMID： 28712823     DOI： 10.1016/j.dsx.2017.07.016

Source DB:  PubMed          Journal:  Diabetes Metab Syndr        ISSN： 1871-4021


  9 in total

1.  Evaluation of Apelin-13 levels in patients with diabetic nephropathy.

Authors:  Gamze İçen; Gülçin Dağlıoğlu; Mehtap Evran
Journal:  Int Urol Nephrol       Date:  2022-08-04       Impact factor: 2.266

2.  Chronic apelin treatment improves hepatic lipid metabolism in obese and insulin-resistant mice by an indirect mechanism.

Authors:  Chantal Bertrand; Jean-Philippe Pradère; Nancy Geoffre; Simon Deleruyelle; Bernard Masri; Jean Personnaz; Sophie Le Gonidec; Aurélie Batut; Katie Louche; Cédric Moro; Philippe Valet; Isabelle Castan-Laurell
Journal:  Endocrine       Date:  2018-02-01       Impact factor: 3.633

3.  Protective and therapeutic effects of two novel strains of Lactobacilli on diabetes-associated disorders induced by a high level of fructose.

Authors:  Naif ALSuhaymi; Ahmed M Darwish; Abd El-Nasser Khattab
Journal:  Mol Biol Rep       Date:  2021-06-02       Impact factor: 2.316

Review 4.  The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer.

Authors:  Marta B Wysocka; Katarzyna Pietraszek-Gremplewicz; Dorota Nowak
Journal:  Front Physiol       Date:  2018-05-23       Impact factor: 4.566

5.  Effect of troxerutin on apelin-13, apelin receptors (APJ), and ovarian histological changes in the offspring of high-fat diet fed rats.

Authors:  Keyvan Mehri; Seyed Mahdi Banan Khojasteh; Banan Khojasteh Seyed Mahdi; Fereshteh Fereshteh; Zohreh Zavvari Oskuye; Hadi Ebrahimi; Roghaye Diba; Parvin Bayandor; Maryam Hosseindoost; Shirin Babri
Journal:  Iran J Basic Med Sci       Date:  2019-06       Impact factor: 2.699

Review 6.  Impact of Incretin-Based Therapies on Adipokines and Adiponectin.

Authors:  Habib Yaribeygi; Mina Maleki; Stephen L Atkin; Tannaz Jamialahmadi; Amirhossein Sahebkar
Journal:  J Diabetes Res       Date:  2021-10-07       Impact factor: 4.011

Review 7.  Possible roles of exercise and apelin against pregnancy complications.

Authors:  Hamed Alizadeh Pahlavani
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-25       Impact factor: 6.055

Review 8.  International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.

Authors:  Cai Read; Duuamene Nyimanu; Thomas L Williams; David J Huggins; Petra Sulentic; Robyn G C Macrae; Peiran Yang; Robert C Glen; Janet J Maguire; Anthony P Davenport
Journal:  Pharmacol Rev       Date:  2019-10       Impact factor: 25.468

9.  Anti-Apoptotic Effect of Apelin in Human Placenta: Studies on BeWo Cells and Villous Explants from Third-Trimester Human Pregnancy.

Authors:  Ewa Mlyczyńska; Małgorzata Myszka; Patrycja Kurowska; Monika Dawid; Tomasz Milewicz; Marta Bałajewicz-Nowak; Paweł Kowalczyk; Agnieszka Rak
Journal:  Int J Mol Sci       Date:  2021-03-09       Impact factor: 5.923
  9 in total

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