Literature DB >> 28712058

Reliance on medicinal plant therapy among cancer patients in Jamaica.

Kimberley Foster1, Novie Younger2, William Aiken3, Doreen Brady-West3, Rupika Delgoda4.   

Abstract

PURPOSE: Patients' perspective of their treatment regime plays a vital role in its success. Recognizing the high prevalence of medicinal plant usage among Jamaicans at large, we investigated the engagement of such remedies by cancer patients, with the aim of uncovering self-medicating habits, perceptions and details of utilized plants.
METHODS: A structured, interviewer-based questionnaire was administered to 100 patients attending the oncology and urology clinics at the University Hospital of the West Indies in Kingston, Jamaica. A method of convenience sampling was employed and the data were analyzed using summary statistics and statistical significance tests.
RESULTS: A large proportion (n = 80, 80%) of interviewed patients, engaged medicinal plants in their treatment regimes. Such habits were independent of person's education, economic status and were higher among the 55-74 age groups (p < 0.05) compared with younger patients. The use of herbs was hinged on the patient's strong sense of tradition and positive perspective of herbal efficacy (88%), fueled by anecdotal accounts from fellow patients. Majority of such users (74.7%) were under concomitant treatment with a prescription medicine, and worryingly, only 15% of patients made their oncologists aware. Annona muricata L. and Petiveria alliacea L. were the most commonly used plants for treating breast and prostate cancers, respectively.
CONCLUSION: A large proportion of Jamaican cancer patients use medicinal plants in self-medicating practices and their perceptions and habits need to be considered by physicians, in the design of safe and effective care regimes.

Entities:  

Keywords:  Breast cancer; Caribbean; Drug–herb interactions; Herbs; Prostate cancer; Traditional medicine

Mesh:

Year:  2017        PMID: 28712058     DOI: 10.1007/s10552-017-0924-9

Source DB:  PubMed          Journal:  Cancer Causes Control        ISSN: 0957-5243            Impact factor:   2.506


  9 in total

1.  In Silico Design and SAR Study of Dibenzyl Trisulfide Analogues for Improved CYP1A1 Inhibition.

Authors:  Nishani Clarke; William Irvine
Journal:  ChemistryOpen       Date:  2022-05       Impact factor: 2.630

2.  Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor.

Authors:  Shaniece Wauchope; Monika A Roy; William Irvine; Isaac Morrison; Eileen Brantley; Maxine Gossell-Williams; Alicia R Timme-Laragy; Rupika Delgoda
Journal:  Toxicol Appl Pharmacol       Date:  2021-03-24       Impact factor: 4.219

3.  Inhibition of Cytochrome P450 Activities by Extracts of Hyptis verticillata Jacq.: Assessment for Potential HERB-Drug Interactions.

Authors:  David Picking; Bentley Chambers; James Barker; Iltaf Shah; Roy Porter; Declan P Naughton; Rupika Delgoda
Journal:  Molecules       Date:  2018-02-15       Impact factor: 4.411

Review 4.  Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review.

Authors:  Islam Rady; Melissa B Bloch; Roxane-Cherille N Chamcheu; Sergette Banang Mbeumi; Md Rafi Anwar; Hadir Mohamed; Abiola S Babatunde; Jules-Roger Kuiate; Felicite K Noubissi; Khalid A El Sayed; G Kerr Whitfield; Jean Christopher Chamcheu
Journal:  Oxid Med Cell Longev       Date:  2018-07-30       Impact factor: 6.543

5.  Potential chemopreventive, anticancer and anti-inflammatory properties of a refined artocarpin-rich wood extract of Artocarpus heterophyllus Lam.

Authors:  Isaac J Morrison; Jianan Zhang; Jingwen Lin; JeAnn E Murray; Roy Porter; Moses K Langat; Nicholas J Sadgrove; James Barker; Guodong Zhang; Rupika Delgoda
Journal:  Sci Rep       Date:  2021-03-25       Impact factor: 4.379

6.  A cross-sectional analysis of investigator needs for non-communicable disease research at the University of the West Indies, Mona.

Authors:  Georgia A Williamson; Shelly Rodrigo; Natalie Guthrie-Dixon; Elizabeth Blackman; J Robert Beck; Ian Hambleton; Althea Bailey; Tomlin Paul; Camille C Ragin; Marshall K Tulloch-Reid
Journal:  Rev Panam Salud Publica       Date:  2021-04-06

7.  Knowledge, attitudes and practices among healthcare professionals regarding complementary alternative medicine use by patients with hypertension and type 2 diabetes mellitus in Western Jamaica.

Authors:  Grace Kwak; Kimberly Gardner; Bolanle Bolaji; Sarah Franklin; Maung Aung; Pauline E Jolly
Journal:  Complement Ther Med       Date:  2021-01-15       Impact factor: 2.446

8.  Selective cytotoxic and anti-metastatic activity in DU-145 prostate cancer cells induced by Annona muricata L. bark extract and phytochemical, annonacin.

Authors:  Kimberley Foster; Omolola Oyenihi; Sunelle Rademan; Joseph Erhabor; Motlalepula Matsabisa; James Barker; Moses K Langat; Amy Kendal-Smith; Helen Asemota; Rupika Delgoda
Journal:  BMC Complement Med Ther       Date:  2020-12-10

9.  Influence of Jamaican Cultural and Religious Beliefs on Adherence to Pharmacotherapy for Non-Communicable Diseases: A Pharmacovigilance Perspective.

Authors:  Robyn Brown; Caryl James Bateman; Maxine Gossell-Williams
Journal:  Front Pharmacol       Date:  2022-03-14       Impact factor: 5.810

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.