Literature DB >> 28712051

A Carbazole-Fused-RhodamineProbe for Detection of HOCl in Living Cells.

Rui Guo1, Qiuan Wang2, Weiying Lin3,4.   

Abstract

A novel fluorescent probe CR-ClO for detection of HOCl based on a carbazole fused rhodamine was designed and synthesized. The probe utilized a HOCl-promoted oxidation reaction, which lead to the ring opening of the compound with a strong enhancement of the fluorescent emission at about 587 nm.The new probe CR-ClO has excellent selectivity and high sensitivity to ClO-,whose detection limit to ClO- is 1.16 × 10-6 M. Furthermore, the new probe has been successfully applied in living cells for detection of ClO-.

Entities:  

Keywords:  Carbazole; Fluorescent probe; HOCl; Rhodamine

Mesh：

Substances：

Year:  2017        PMID： 28712051     DOI： 10.1007/s10895-017-2134-y

Source DB:  PubMed          Journal:  J Fluoresc        ISSN： 1053-0509            Impact factor:   2.217


  23 in total

Review 1.  Fluorescent chemosensors based on spiroring-opening of xanthenes and related derivatives.

Authors:  Xiaoqiang Chen; Tuhin Pradhan; Fang Wang; Jong Seung Kim; Juyoung Yoon
Journal:  Chem Rev       Date:  2011-10-31       Impact factor: 60.622

2.  Synthesis and applications of Rhodamine derivatives as fluorescent probes.

Authors:  Mariana Beija; Carlos A M Afonso; José M G Martinho
Journal:  Chem Soc Rev       Date:  2009-04-27       Impact factor: 54.564

3.  A Unique "Integration" Strategy for the Rational Design of Optically Tunable Near-Infrared Fluorophores.

Authors:  Hua Chen; Baoli Dong; Yonghe Tang; Weiying Lin
Journal:  Acc Chem Res       Date:  2017-05-11       Impact factor: 22.384

4.  Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach.

Authors:  Corin Storkey; Michael J Davies; David I Pattison
Journal:  Free Radic Biol Med       Date:  2014-05-01       Impact factor: 7.376

Review 5.  The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids.

Authors:  C M Spickett; A Jerlich; O M Panasenko; J Arnhold; A R Pitt; T Stelmaszyńska; R J Schaur
Journal:  Acta Biochim Pol       Date:  2000       Impact factor: 2.149

6.  Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins.

Authors:  E Malle; G Waeg; R Schreiber; E F Gröne; W Sattler; H J Gröne
Journal:  Eur J Biochem       Date:  2000-07

Review 7.  Hypochlorite-induced oxidation of amino acids, peptides and proteins.

Authors:  C L Hawkins; D I Pattison; M J Davies
Journal:  Amino Acids       Date:  2003-07-29       Impact factor: 3.520

8.  5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay.

Authors:  Qing Jiang; Ben C Blount; Bruce N Ames
Journal:  J Biol Chem       Date:  2003-06-16       Impact factor: 5.157

9.  Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry.

Authors:  J J van den Berg; C C Winterbourn; F A Kuypers
Journal:  J Lipid Res       Date:  1993-11       Impact factor: 5.922

Review 10.  Reaction-based small-molecule fluorescent probes for chemoselective bioimaging.

Authors:  Jefferson Chan; Sheel C Dodani; Christopher J Chang
Journal:  Nat Chem       Date:  2012-12       Impact factor: 24.427
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