Literature DB >> 2871188

Sulphasalazine in the treatment of juvenile rheumatoid arthritis: a preliminary open trial.

H Ozdogan, M Turunç, B Deringöl, S Yurdakul, H Yazici.   

Abstract

Sulphasalazine was administered to 18 patients with juvenile rheumatoid arthritis (JRA). The mean duration of therapy was 7.8 +/- 2.6 months. There was significant improvement in all clinical variables and erythrocyte sedimentation rate. Five children developed minor and transient side effects. Medication was discontinued in 3 patients: one because of leukopenia, 2 for lack of effect. These results suggest that sulphasalazine is an effective and relatively safe drug which may prove to be a useful second line agent in the management of JRA.

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Year:  1986        PMID: 2871188

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  11 in total

Review 1.  Pharmacological management of juvenile rheumatoid arthritis.

Authors:  C D Rose; R A Doughty
Journal:  Drugs       Date:  1992-06       Impact factor: 9.546

2.  Sulphasalazine induced hepatitis in adult Still's disease.

Authors:  J Crowley; R D Situnayake
Journal:  Ann Rheum Dis       Date:  1992-11       Impact factor: 19.103

Review 3.  Medical management of children with juvenile rheumatoid arthritis.

Authors:  J T Cassidy
Journal:  Drugs       Date:  1999-11       Impact factor: 9.546

Review 4.  Juvenile rheumatoid arthritis: therapeutic perspectives.

Authors:  Ian C Chikanza
Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

5.  HLA B27 allele types in homogeneous groups of juvenile idiopathic arthritis patients in Latvia.

Authors:  Valda Stanevicha; Jelena Eglite; Dace Zavadska; Arturs Sochnevs; Arina Lazareva; Dinara Guseinova; Ruta Shantere; Dace Gardovska
Journal:  Pediatr Rheumatol Online J       Date:  2010-10-14       Impact factor: 3.054

Review 6.  Clinical pharmacokinetics of drugs used in juvenile arthritis.

Authors:  K J Skeith; F Jamali
Journal:  Clin Pharmacokinet       Date:  1991-08       Impact factor: 6.447

7.  Sulphasalazine in the treatment of children with chronic arthritis.

Authors:  J L Huang; L C Chen
Journal:  Clin Rheumatol       Date:  1998       Impact factor: 2.980

8.  Sulphasalazine induced hepatitis in juvenile rheumatoid arthritis.

Authors:  D Caspi; D Fuchs; M Yaron
Journal:  Ann Rheum Dis       Date:  1992-02       Impact factor: 19.103

Review 9.  A risk-benefit assessment of slow-acting antirheumatic drugs in rheumatoid arthritis.

Authors:  A A Kalla; A F Tooke; E Bhettay; O L Meyers
Journal:  Drug Saf       Date:  1994-07       Impact factor: 5.606

10.  Sulphasalazine in the treatment of pauciarticular-onset juvenile chronic arthritis.

Authors:  A Gedalia; J Barash; J Press; D Buskila
Journal:  Clin Rheumatol       Date:  1993-12       Impact factor: 2.980

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