Literature DB >> 28711144

Genetics of Juvenile Idiopathic Arthritis.

Aimee O Hersh1, Sampath Prahalad2.   

Abstract

Juvenile idiopathic arthritis (JIA) affects approximately 1 in 1000 US children. The cause of JIA is most likely multifactorial and due to an interplay of genetics and environmental factors. This article summarizes the known genetic risk factors for JIA that have been identified, and in some cases replicated, using a variety of methods, including genomewide association and candidate gene association studies. A brief discussion regarding pharmacogenomics and studies to data linking genetics to treatment response and outcomes is included.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Association; Genetics; Genomewide; Juvenile idiopathic arthritis

Mesh：

Year:  2017        PMID： 28711144     DOI： 10.1016/j.rdc.2017.04.007

Source DB:  PubMed          Journal:  Rheum Dis Clin North Am        ISSN： 0889-857X            Impact factor:   2.670


  7 in total

1.  Juvenile Idiopathic Arthritis Associated with Combined JP-HHT Syndrome: A Novel Phenotype Associated with a Novel Variant in SMAD4.

Authors:  Juliet Chhay Bishop; Jacquelyn Francis Britton; Anne M Murphy; Sangeeta Sule; Sally Mitchell; Clifford Takemoto; Joseph M Collaco; Wikrom Karnsakul; Carmelo Cuffari; Edith Dietz; Joann Bodurtha
Journal:  J Pediatr Genet       Date:  2017-12-29

2.  Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci.

Authors:  Kaiyu Jiang; Haeja Kessler; Yungki Park; Marc Sudman; Susan D Thompson; James N Jarvis
Journal:  PLoS One       Date:  2020-07-30       Impact factor: 3.240

Review 3.  Using Chromatin Architecture to Understand the Genetics and Transcriptomics of Juvenile Idiopathic Arthritis.

Authors:  Haeja Kessler; Kaiyu Jiang; James N Jarvis
Journal:  Front Immunol       Date:  2018-12-14       Impact factor: 7.561

Review 4.  Review of environmental factors and juvenile idiopathic arthritis.

Authors:  Daniel B Horton; Susan Shenoi
Journal:  Open Access Rheumatol       Date:  2019-11-06

Review 5.  B Cells on the Stage of Inflammation in Juvenile Idiopathic Arthritis: Leading or Supporting Actors in Disease Pathogenesis?

Authors:  Rita A Moura; João Eurico Fonseca
Journal:  Front Med (Lausanne)       Date:  2022-04-04

6.  A Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Susceptibility Genes for Juvenile Idiopathic Arthritis in Asia and Europe.

Authors:  Jiawen Xu; Jun Ma; Yi Zeng; Haibo Si; Yuangang Wu; Shaoyun Zhang; Bin Shen
Journal:  Front Immunol       Date:  2022-07-28       Impact factor: 8.786

7.  Gut microbiota in children with juvenile idiopathic arthritis: characteristics, biomarker identification, and usefulness in clinical prediction.

Authors:  Xubo Qian; Yong-Xin Liu; Xiaohong Ye; Wenjie Zheng; Shaoxia Lv; Miaojun Mo; Jinjing Lin; Wenqin Wang; Weihan Wang; Xianning Zhang; Meiping Lu
Journal:  BMC Genomics       Date:  2020-04-07       Impact factor: 3.969
  7 in total

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