Anthony Dohan1,2, Mourad Boudiaf3, Xavier Dray4,5, Elia Samaha6, Christophe Cellier6,7, Marine Camus7,8, Clarisse Eveno9,10, Raphael Dautry3, Philippe Soyer9,11. 1. Department of Body and Interventional Imaging, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France. anthony.dohan@aphp.fr. 2. Université Sorbonne Paris Cité, Paris Diderot, INSERM UMR 965, 2 Rue Ambroise Paré, 75010, Paris, France. anthony.dohan@aphp.fr. 3. Department of Body and Interventional Imaging, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France. 4. Department of Digestive Diseases, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, 184 Rue du Faubourg Saint-Antoine, 75012, Paris, France. 5. Sorbonne Université, Paris, France. 6. Gastroenterology and Endoscopy Unit, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, 20 Rue Leblanc, 75015, Paris, France. 7. Université Sorbonne Paris Cité, Paris Descartes, Paris, France. 8. Department of Gastroenterology, Hôpital Cochin - Assistance Publique-Hôpitaux de Paris, 27 Rue du Faubourg Saint-Jacques, 75014, Paris, France. 9. Université Sorbonne Paris Cité, Paris Diderot, INSERM UMR 965, 2 Rue Ambroise Paré, 75010, Paris, France. 10. Department of Surgical Oncologic and Digestive Unit, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75475, Paris, France. 11. Department of Body and Interventional Imaging, Hôpital Cochin - Assistance Publique-Hôpitaux de Paris, 27 Rue du Faubourg Saint-Jacques, 75014, Paris, France.
Abstract
PURPOSE: The aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs). PATIENTS AND METHODS: After IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE). Performance of VE was evaluated through comparison with the current standard of reference, including surgery and/or enteroscopy and/or follow-up. RESULTS: Tolerance was excellent in 16/17 patients (94%). The radiation dose was lower for VE than for CTE (533 ± 282 vs. 974 ± 505 mGy.cm; p = 0.002). With VE, a total of 25 polyps >5 mm in size were depicted in 12/17 patients. On a per-lesion analysis, sensitivity and positive predictive value of VE were 92.0% and 92.0%, respectively. On a per-segment analysis VE had a sensitivity and specificity of 95.0% and 87.0%, respectively. CONCLUSION: Our preliminary study suggests that VE is a feasible and well-tolerated technique with high sensitivity and specificity for the diagnosis of SBT. KEY POINTS: • Virtual enteroscopy is feasible and well tolerated. • Virtual enteroscopy appears to be accurate for detection of small-bowel tumours. • Sensitivity and PPV of virtual enteroscopy is 92.0% and 92.0%. • Radiation dose is lower with virtual enteroscopy compared to MDCT-enteroclysis.
PURPOSE: The aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs). PATIENTS AND METHODS: After IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE). Performance of VE was evaluated through comparison with the current standard of reference, including surgery and/or enteroscopy and/or follow-up. RESULTS: Tolerance was excellent in 16/17 patients (94%). The radiation dose was lower for VE than for CTE (533 ± 282 vs. 974 ± 505 mGy.cm; p = 0.002). With VE, a total of 25 polyps >5 mm in size were depicted in 12/17 patients. On a per-lesion analysis, sensitivity and positive predictive value of VE were 92.0% and 92.0%, respectively. On a per-segment analysis VE had a sensitivity and specificity of 95.0% and 87.0%, respectively. CONCLUSION: Our preliminary study suggests that VE is a feasible and well-tolerated technique with high sensitivity and specificity for the diagnosis of SBT. KEY POINTS: • Virtual enteroscopy is feasible and well tolerated. • Virtual enteroscopy appears to be accurate for detection of small-bowel tumours. • Sensitivity and PPV of virtual enteroscopy is 92.0% and 92.0%. • Radiation dose is lower with virtual enteroscopy compared to MDCT-enteroclysis.
Authors: J Greffier; F Macri; A Larbi; A Fernandez; E Khasanova; F Pereira; C Mekkaoui; J P Beregi Journal: Diagn Interv Imaging Date: 2015-03-19 Impact factor: 4.026
Authors: Stijn J B Van Weyenberg; Martijn R Meijerink; Maarten A J M Jacobs; Cornelis van Kuijk; Chris J Mulder; Jan Hein T M van Waesberghe Journal: Radiology Date: 2011-02-17 Impact factor: 11.105