Sissi Cao 1 , Dongmei Sun 2 Show Affiliations »
Abstract
BACKGROUND: Influenza vaccinations are commonly administered and effectively prevent influenza. Most vaccine reactions are mild and self-limiting with few reported cases of vasculitis. We present a case of vasculitis post-vaccination unique for its dramatic visual presentation and rapid response to treatment with the aim to emphasise possible causation and timely treatment. CASE PRESENTATION: This is a case of a 60-year-old man with chronic idiopathic pulmonary fibrosis, with fever, arthralgias and rash characterised by extensive erythematous plaques on his limbs and trunk 5 days after influenza vaccination. Skin biopsy revealed leucocytoclastic vasculitis. Rash and symptoms resolved 10 days after initiating treatment with oral prednisone. CONCLUSIONS: Influenza vaccines can potentially precipitate cutaneous vasculitis, and timely treatment reduces morbidity in the elderly. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
BACKGROUND: Influenza vaccinations are commonly administered and effectively prevent influenza. Most vaccine reactions are mild and self-limiting with few reported cases of vasculitis . We present a case of vasculitis post-vaccination unique for its dramatic visual presentation and rapid response to treatment with the aim to emphasise possible causation and timely treatment. CASE PRESENTATION: This is a case of a 60-year-old man with chronic idiopathic pulmonary fibrosis , with fever , arthralgias and rash characterised by extensive erythematous plaques on his limbs and trunk 5 days after influenza vaccination. Skin biopsy revealed leucocytoclastic vasculitis . Rash and symptoms resolved 10 days after initiating treatment with oral prednisone . CONCLUSIONS: Influenza vaccines can potentially precipitate cutaneous vasculitis , and timely treatment reduces morbidity in the elderly. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Entities: Chemical
Disease
Species
Keywords:
Immunological Products And Vaccines; Vasculitis
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Year: 2017
PMID： 28710188 PMCID： PMC5534821 DOI： 10.1136/bcr-2016-217755
Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X