| Literature DB >> 28708573 |
Thanh Tung Bui1, Thanh Hai Nguyen1.
Abstract
Alzheimer's disease (AD) is related to increasing age. It is mainly characterized by progressive neurodegenerative disease, which damages memory and cognitive function. Natural products offer many options to reduce the progress and symptoms of many kinds of diseases, including AD. Meanwhile, natural compound structures, including lignans, flavonoids, tannins, polyphenols, triterpenes, sterols, and alkaloids, have anti-inflammatory, antioxidant, anti-amyloidogenic, and anticholinesterase activities. In this review, we summarize the pathogenesis and targets for treatment of AD. We also present several medicinal plants and isolated compounds that are used for preventing and reducing symptoms of AD.Entities:
Keywords: Alzheimer’s disease; acetylcholinesterase enzyme; natural product; β-amyloid
Mesh:
Substances:
Year: 2017 PMID: 28708573 DOI: 10.1515/jbcpp-2016-0147
Source DB: PubMed Journal: J Basic Clin Physiol Pharmacol ISSN: 0792-6855