Literature DB >> 28708573

Natural product for the treatment of Alzheimer's disease.

Thanh Tung Bui1, Thanh Hai Nguyen1.   

Abstract

Alzheimer's disease (AD) is related to increasing age. It is mainly characterized by progressive neurodegenerative disease, which damages memory and cognitive function. Natural products offer many options to reduce the progress and symptoms of many kinds of diseases, including AD. Meanwhile, natural compound structures, including lignans, flavonoids, tannins, polyphenols, triterpenes, sterols, and alkaloids, have anti-inflammatory, antioxidant, anti-amyloidogenic, and anticholinesterase activities. In this review, we summarize the pathogenesis and targets for treatment of AD. We also present several medicinal plants and isolated compounds that are used for preventing and reducing symptoms of AD.

Entities:  

Keywords:  Alzheimer’s disease; acetylcholinesterase enzyme; natural product; β-amyloid

Mesh:

Substances:

Year:  2017        PMID: 28708573     DOI: 10.1515/jbcpp-2016-0147

Source DB:  PubMed          Journal:  J Basic Clin Physiol Pharmacol        ISSN: 0792-6855


  19 in total

1.  Effects of Astaxanthin from Shrimp Shell on Oxidative Stress and Behavior in Animal Model of Alzheimer's Disease.

Authors:  Takunrat Taksima; Pennapa Chonpathompikunlert; Morakot Sroyraya; Pilaiwanwadee Hutamekalin; Maruj Limpawattana; Wanwimol Klaypradit
Journal:  Mar Drugs       Date:  2019-11-04       Impact factor: 5.118

2.  Natural Products and Neuroprotection.

Authors:  Cristina Angeloni; David Vauzour
Journal:  Int J Mol Sci       Date:  2019-11-07       Impact factor: 5.923

Review 3.  Molecular Mechanisms of Anticancer Activities of Puerarin.

Authors:  Bashir Ahmad; Suliman Khan; Yang Liu; Mengzhou Xue; Ghulam Nabi; Sunjeet Kumar; Mohammed Alshwmi; Abdul Wakeel Qarluq
Journal:  Cancer Manag Res       Date:  2020-01-08       Impact factor: 3.989

4.  Ficus erecta Thunb. Leaves Ameliorate Cognitive Deficit and Neuronal Damage in a Mouse Model of Amyloid-β-Induced Alzheimer's Disease.

Authors:  Eunjin Sohn; Yu Jin Kim; Joo-Hwan Kim; Soo-Jin Jeong
Journal:  Front Pharmacol       Date:  2021-04-15       Impact factor: 5.810

5.  A Novel Peroxidase Mimics and Ameliorates Alzheimer's Disease-Related Pathology and Cognitive Decline in Mice.

Authors:  Jia Xu; Kai Wang; Ye Yuan; Hui Li; Ruining Zhang; Shuwen Guan; Liping Wang
Journal:  Int J Mol Sci       Date:  2018-10-24       Impact factor: 5.923

6.  Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay.

Authors:  Aimi Syamima Abdul Manap; Amelia Cheng Wei Tan; Weng Hhin Leong; Adeline Yoke Yin Chia; Shantini Vijayabalan; Aditya Arya; Eng Hwa Wong; Farzana Rizwan; Umesh Bindal; Shajan Koshy; Priya Madhavan
Journal:  Front Aging Neurosci       Date:  2019-08-27       Impact factor: 5.750

7.  The Impact of Natural Compounds on S-Shaped Aβ42 Fibril: From Molecular Docking to Biophysical Characterization.

Authors:  Stefano Muscat; Lorenzo Pallante; Filip Stojceski; Andrea Danani; Gianvito Grasso; Marco Agostino Deriu
Journal:  Int J Mol Sci       Date:  2020-03-16       Impact factor: 5.923

Review 8.  Cognitive Function and Consumption of Fruit and Vegetable Polyphenols in a Young Population: Is There a Relationship?

Authors:  Juan Ángel Carrillo; M Pilar Zafrilla; Javier Marhuenda
Journal:  Foods       Date:  2019-10-17

9.  Krill Oil Attenuates Cognitive Impairment by the Regulation of Oxidative Stress and Neuronal Apoptosis in an Amyloid β-Induced Alzheimer's Disease Mouse Model.

Authors:  Ji Hyun Kim; Hui Wen Meng; Mei Tong He; Ji Myung Choi; Dongjun Lee; Eun Ju Cho
Journal:  Molecules       Date:  2020-08-28       Impact factor: 4.411

10.  Isoforsythiaside Attenuates Alzheimer's Disease via Regulating Mitochondrial Function Through the PI3K/AKT Pathway.

Authors:  Chunyue Wang; Jie Hao; Xin Liu; Chenliang Li; Xuyang Yuan; Robert J Lee; Tian Bai; Di Wang
Journal:  Int J Mol Sci       Date:  2020-08-08       Impact factor: 5.923

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