Literature DB >> 28705920

Nephron Remodeling Underlies Hyperkalemia in Familial Hyperkalemic Hypertension.

James A McCormick1, David H Ellison2,3.   

Abstract

Entities:  

Keywords:  Gordon Syndrome; chloride; hyperkalemia; sodium; thiazide

Mesh：

Year:  2017        PMID： 28705920      PMCID： PMC5576953          DOI： 10.1681/ASN.2017060660

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


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8.  Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.

Authors:  P Richard Grimm; Richard Coleman; Eric Delpire; Paul A Welling
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9.  Acute inhibition of NCC does not activate distal electrogenic Na+ reabsorption or kaliuresis.

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1.  Familial hyperkalemic hypertension: hyperkalemia not hypertension defines dominant KLHL3 disease and may permit earlier recognition and tailored therapy.

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