Kiyuri Naicker1, Simon Øverland2, Jeffrey A Johnson3, Douglas Manuel4, Jens C Skogen5, Børge Sivertsen6, Ian Colman7. 1. School of Public Health and Preventive Medicine, University of Ottawa, Ontario Canada. 2. Department of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway; Department of Psychosocial Science, University of Bergen, Norway. 3. School of Public Health, University of Alberta, Edmonton, Alberta, Canada. 4. Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. 5. Department of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway; Center for Alcohol and Drug Research, Stavanger University Hospital, Stavanger, Norway. 6. Department of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway; Department Research and Innovation, Helse Fonna HF, Haugesund, Norway; The Regional Centre for Child and Youth Mental Health and Child Welfare, Uni Research Health, Bergen, Norway. 7. School of Public Health and Preventive Medicine, University of Ottawa, Ontario Canada. Electronic address: icolman@uottawa.ca.
Abstract
OBJECTIVE: To determine if symptoms of depression and anxiety are differentially associated with clinical diabetes measures and self-management behaviours in individuals with Type 2 diabetes, and whether these associations vary by patient sex. RESEARCH DESIGN AND METHODS: A cross-sectional analysis using data from 2035 adults with Type 2 diabetes in the Nord-Trøndelag Health Study. Multivariate logistic regression was used to explore associations between symptoms of depression and anxiety and waist girth, HDL cholesterol, systolic blood pressure, triglycerides, c-reactive protein, glycemic control, diet adherence, exercise, glucose monitoring, foot checks for ulcers, and the subjective patient experience. Analyses were stratified by sex. RESULTS: Depression was associated with a lower likelihood of avoiding saturated fats (OR=0.20 [95% CI: 0.06, 0.68]) and increased odds of physical inactivity (OR=1.69 [95% CI: 1.37, 2.72]). Anxiety was associated with increased odds of eating vegetables (OR=1.66 [95% CI: 1.02, 2.73]), and an over two-fold increase of feeling that having diabetes is difficult. In women, anxiety was associated with elevated c-reactive protein levels (OR=1.57 [95% CI: 1.05, 2.34]). In men, depressive symptoms were associated with elevated HbA1c (OR=5.00 [95% CI: 1.15, 8.23). CONCLUSIONS: Symptoms of depression and anxiety were differentially associated with some key diabetes-related measures. Our results suggest sex-specific differences with respect to two important clinical outcomes (i.e., anxiety and CRP in women and depression and glycemic control in men). These findings should alert practitioners to the importance of detection and management of psychological symptoms in individuals with Type 2 diabetes.
OBJECTIVE: To determine if symptoms of depression and anxiety are differentially associated with clinical diabetes measures and self-management behaviours in individuals with Type 2 diabetes, and whether these associations vary by patient sex. RESEARCH DESIGN AND METHODS: A cross-sectional analysis using data from 2035 adults with Type 2 diabetes in the Nord-Trøndelag Health Study. Multivariate logistic regression was used to explore associations between symptoms of depression and anxiety and waist girth, HDL cholesterol, systolic blood pressure, triglycerides, c-reactive protein, glycemic control, diet adherence, exercise, glucose monitoring, foot checks for ulcers, and the subjective patient experience. Analyses were stratified by sex. RESULTS:Depression was associated with a lower likelihood of avoiding saturated fats (OR=0.20 [95% CI: 0.06, 0.68]) and increased odds of physical inactivity (OR=1.69 [95% CI: 1.37, 2.72]). Anxiety was associated with increased odds of eating vegetables (OR=1.66 [95% CI: 1.02, 2.73]), and an over two-fold increase of feeling that having diabetes is difficult. In women, anxiety was associated with elevated c-reactive protein levels (OR=1.57 [95% CI: 1.05, 2.34]). In men, depressive symptoms were associated with elevated HbA1c (OR=5.00 [95% CI: 1.15, 8.23). CONCLUSIONS: Symptoms of depression and anxiety were differentially associated with some key diabetes-related measures. Our results suggest sex-specific differences with respect to two important clinical outcomes (i.e., anxiety and CRP in women and depression and glycemic control in men). These findings should alert practitioners to the importance of detection and management of psychological symptoms in individuals with Type 2 diabetes.
Authors: Mohammed A Batais; Abdulaziz F Alfraiji; Abdulrahman Abdullah Alyahya; Ouf Abdullatif Aloofi; Mohammad Khalid Almashouq; Khalid Saeed Alshehri; Abdulrahman Mohammed Almizel; Mohammed Taraheeb Alotaibi; Fahad D Alosaimi Journal: Front Psychol Date: 2021-12-22
Authors: Emma A Nieuwenhuijse; Jeroen N Struijs; Stephen P Sutch; Mattijs E Numans; Rimke C Vos Journal: Diabet Med Date: 2022-04-01 Impact factor: 4.213