Literature DB >> 28704657

Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly.

Robyn S Klein1.   

Abstract

Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28704657      PMCID: PMC5775962          DOI: 10.1016/j.chom.2017.06.015

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  11 in total

1.  Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3.

Authors:  Jason Dang; Shashi Kant Tiwari; Gianluigi Lichinchi; Yue Qin; Veena S Patil; Alexey M Eroshkin; Tariq M Rana
Journal:  Cell Stem Cell       Date:  2016-05-06       Impact factor: 24.633

2.  Characterization of the RNA-binding protein Musashi1 in zebrafish.

Authors:  Shinsuke Shibata; Masahiko Umei; Hironori Kawahara; Masato Yano; Shinji Makino; Hideyuki Okano
Journal:  Brain Res       Date:  2012-02-03       Impact factor: 3.252

3.  Cytogenetic modifications induced in human diploid cells by mixed infection with measles and cytomegalic virus.

Authors:  C Cernescu; D Rojanschi
Journal:  Virologie       Date:  1981 Jul-Sep       Impact factor: 0.474

4.  Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease.

Authors:  Benjamin M Akiyama; Hannah M Laurence; Aaron R Massey; David A Costantino; Xuping Xie; Yujiao Yang; Pei-Yong Shi; Jay C Nix; J David Beckham; Jeffrey S Kieft
Journal:  Science       Date:  2016-11-10       Impact factor: 47.728

5.  Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication.

Authors:  Pavithra L Chavali; Lovorka Stojic; Luke W Meredith; Nimesh Joseph; Michael S Nahorski; Thomas J Sanford; Trevor R Sweeney; Ben A Krishna; Myra Hosmillo; Andrew E Firth; Richard Bayliss; Carlo L Marcelis; Susan Lindsay; Ian Goodfellow; C Geoffrey Woods; Fanni Gergely
Journal:  Science       Date:  2017-06-01       Impact factor: 47.728

Review 6.  Microcephalin: a causal link between impaired damage response signalling and microcephaly.

Authors:  Mark O'Driscoll; Andrew P Jackson; Penny A Jeggo
Journal:  Cell Cycle       Date:  2006-10-16       Impact factor: 4.534

Review 7.  Musashi1: an RBP with versatile functions in normal and cancer stem cells.

Authors:  Robert I Glazer; Dat T Vo; Luiz O F Penalva
Journal:  Front Biosci (Landmark Ed)       Date:  2012-01-01

Review 8.  Molecular and cellular basis of autosomal recessive primary microcephaly.

Authors:  Marine Barbelanne; William Y Tsang
Journal:  Biomed Res Int       Date:  2014-12-08       Impact factor: 3.411

9.  Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic.

Authors:  Zheng Zhu; Jasper Fuk-Woo Chan; Kah-Meng Tee; Garnet Kwan-Yue Choi; Susanna Kar-Pui Lau; Patrick Chiu-Yat Woo; Herman Tse; Kwok-Yung Yuen
Journal:  Emerg Microbes Infect       Date:  2016-03-16       Impact factor: 7.163

10.  Zika virus and microcephaly: why is this situation a PHEIC?

Authors:  David L Heymann; Abraham Hodgson; Amadou Alpha Sall; David O Freedman; J Erin Staples; Fernando Althabe; Kalpana Baruah; Ghazala Mahmud; Nyoman Kandun; Pedro F C Vasconcelos; Silvia Bino; K U Menon
Journal:  Lancet       Date:  2016-02-11       Impact factor: 79.321

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