Literature DB >> 28703950

Randomized Controlled Trial of Web-Based Psychoeducation for Women With Borderline Personality Disorder.

Mary C Zanarini1,2,3, Lindsey C Conkey2, Christina M Temes2,3, Garrett M Fitzmaurice2,3.   

Abstract

OBJECTIVE: To determine if internet-based psychoeducation for borderline personality disorder is effective in reducing symptom severity and improving psychosocial functioning.
METHODS: Eighty women who met DSM-IV criteria for borderline personality disorder were randomly assigned either to the internet-based psychoeducation treatment group (n = 40) or to the internet-based control group with no psychoeducation (n = 40). Recruitment was conducted from July 2013 to March 2015. Subjects participated in 15 assessment periods that were divided into an acute phase (weeks 1-12) and a maintenance phase (months 6, 9, and 12). Main outcomes were assessed using the Zanarini Rating Scale for Borderline Personality Disorder.
RESULTS: In the acute phase, women in the treatment group were found to have a significant decline in their scores on all 10 outcomes studied, while women in the control group had a significant decline on 7 of these outcomes. Two between-group differences were found to be significant-those in the treatment group reported a significantly greater decline in their impulsivity (z = -1.98, P = .048) and a significantly greater increase in their psychosocial functioning (z = -1.97, P = .049) than those in the control group. In the maintenance phase, those in the treatment group were found to have a significant decline in their scores on 9 of the 10 outcomes studied, while those in the control group had a significant decline in 3 of these outcomes. In terms of between-group differences, those in the treatment group reported a significantly greater decline in all 5 studied areas of borderline psychopathology: affective symptoms (z = -2.31, P = .021), cognitive symptoms (z = -3.20, P = .001), impulsivity (z = -2.44, P = .015), interpersonal difficulties (z = -2.15, P = .032), and overall borderline personality disorder symptoms (z = -2.11, P = .035).
CONCLUSIONS: Taken together, these results suggest that internet-based psychoeducation is an effective form of early treatment for reducing the symptom severity of borderline personality disorder for periods up to 1 year. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01719731. © Copyright 2018 Physicians Postgraduate Press, Inc.

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Mesh:

Year:  2018        PMID: 28703950      PMCID: PMC5764827          DOI: 10.4088/JCP.16m11153

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


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7.  Topiramate treatment of aggression in female borderline personality disorder patients: a double-blind, placebo-controlled study.

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Journal:  J Clin Psychiatry       Date:  2004-11       Impact factor: 4.384

8.  Amitriptyline versus haloperidol in borderlines: final outcomes and predictors of response.

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7.  Smartphone applications targeting borderline personality disorder symptoms: a systematic review and meta-analysis.

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Review 10.  Designing a range of mentalizing interventions for young people using a clinical staging approach to borderline pathology.

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