Literature DB >> 28702539

A divergent [5+2] cascade approach to bicyclo[3.2.1]octanes: facile synthesis of ent-kaurene and cedrene-type skeletons.

Chi He1, Zengbing Bai2, Jialei Hu1, Bingnan Wang1, Hujun Xie3, Lei Yu2, Hanfeng Ding1.   

Abstract

A solvent-dependent oxidative dearomatization-induced divergent [5+2] cascade approach to bicyclo[3.2.1]octanes was described. This novel protocol enables a facile synthesis of a series of diversely functionalized ent-kaurene and cedrene-type skeletons in good yields and excellent diastereoselectivities.

Entities:  

Year:  2017        PMID： 28702539     DOI： 10.1039/c7cc04292b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Use of hydroxylamines, hydroxamic acids, oximes and amines as nucleophiles in the Zbiral oxidative deamination of N-acetyl neuraminic acid. Isolation and characterization of novel mono- and disubstitution products.

Authors:  Mohammed Hawsawi; Michael G Pirrone; Anura Wickramasinghe; David Crich
Journal:  Carbohydr Res       Date:  2020-01-25       Impact factor: 2.104

2.  Scalable synthesis enabling multilevel bio-evaluations of natural products for discovery of lead compounds.

Authors:  Lizhi Zhu; Wenjing Ma; Mengxun Zhang; Magnolia Muk-Lan Lee; Wing-Yan Wong; Brandon Dow Chan; Qianqian Yang; Wing-Tak Wong; William Chi-Shing Tai; Chi-Sing Lee
Journal:  Nat Commun       Date:  2018-03-29       Impact factor: 14.919
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.