Literature DB >> 2870156

The effect of the molecular weight of polyethylene glycol on the bioavailability of paracetamol-polyethylene glycol solid dispersions.

J L Vila-Jato, J Blanco, M J Alonso.   

Abstract

A controlled study of the bioavailability of paracetamol in solid dispersion with PEG 6000, 10000 and 20000 has been made. The total amount of paracetamol excreted in urine increased with molecular weight of the PEG, but the rate of absorption of the drug was unaffected.

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Year:  1986        PMID： 2870156     DOI： 10.1111/j.2042-7158.1986.tb04525.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  1 in total

1.  Biopharmaceutical characterization of sustained release matrix tablets based on novel carbomer polymers: formulation and in vivo investigation.

Authors:  Parojcić Jelena; Zorica Djurić; Milica Jovanović; Svetlana Ibrić; Vesna Kilibarda; Dusan Jovanović; Ivan Kovac Evic
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Jan-Jun       Impact factor: 2.441
  1 in total

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