Audree Tadros1, Brittany Arditi2, Christina Weltz1, Elisa Port1, Laurie R Margolies3, Hank Schmidt4. 1. Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Dubin Breast Center at the Tisch Cancer Institute, New York, NY, United States. 2. Dubin Breast Center at the Tisch Cancer Institute, New York, NY, United States. 3. Dubin Breast Center at the Tisch Cancer Institute, New York, NY, United States; Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States. 4. Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Dubin Breast Center at the Tisch Cancer Institute, New York, NY, United States. Electronic address: hank.schmidt@mountsinai.org.
Abstract
PURPOSE: To determine the utility and rate of biopsy in women with a positive history of breast cancer screened with MRI. METHODS: Retrospective review of 491 breast MRI screening examinations in women with a personal history of breast cancer. RESULTS: In total, 107 biopsies were performed, an average of 0.09 biopsies per person year. The positive predictive value for biopsies prompted by MRI findings was 0.24 (95% C.I. 0.10-0.38). Eight of the nine subsequent cancers were initially identified on screening MRI alone. CONCLUSION: Surveillance MRI in breast cancer survivors may increase detection of subsequent cancers while increasing rate of biopsy.
PURPOSE: To determine the utility and rate of biopsy in women with a positive history of breast cancer screened with MRI. METHODS: Retrospective review of 491 breast MRI screening examinations in women with a personal history of breast cancer. RESULTS: In total, 107 biopsies were performed, an average of 0.09 biopsies per person year. The positive predictive value for biopsies prompted by MRI findings was 0.24 (95% C.I. 0.10-0.38). Eight of the nine subsequent cancers were initially identified on screening MRI alone. CONCLUSION: Surveillance MRI in breast cancer survivors may increase detection of subsequent cancers while increasing rate of biopsy.