Literature DB >> 28699077

Focusing attention on ancestral diversity within genomics research: a potential means for promoting equity in the provision of genomics based healthcare services in developing countries.

Nirmala D Sirisena1, Vajira H W Dissanayake2.   

Abstract

Although we are well into the second decade after the completion of the International Human Genome Project, genomic research has failed to fully represent the diverse ancestry of global populations. The resultant healthcare challenges faced by populations underrepresented in genomic research needs to be tackled by the global scientific community. In this paper, we address several major factors which have contributed to the existing health disparity and put forward a combination of scientific and political interventions needed to bring about a change that will ensure all global populations benefit equally from the advances made in genomic medicine and research.

Entities:  

Keywords:  Ancestry; Diversity; Ethnic; Genomics; Healthcare; Research

Year:  2017        PMID: 28699077      PMCID: PMC5614882          DOI: 10.1007/s12687-017-0311-y

Source DB:  PubMed          Journal:  J Community Genet        ISSN: 1868-310X


  24 in total

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Journal:  J Community Genet       Date:  2013-08-10

Review 2.  Global implementation of genomic medicine: We are not alone.

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Journal:  Sci Transl Med       Date:  2015-06-03       Impact factor: 17.956

Review 3.  Conceptualizing and categorizing race and ethnicity in health services research.

Authors:  Marvella E Ford; P Adam Kelly
Journal:  Health Serv Res       Date:  2005-10       Impact factor: 3.402

4.  Genetic Misdiagnoses and the Potential for Health Disparities.

Authors:  Arjun K Manrai; Birgit H Funke; Heidi L Rehm; Morten S Olesen; Bradley A Maron; Peter Szolovits; David M Margulies; Joseph Loscalzo; Isaac S Kohane
Journal:  N Engl J Med       Date:  2016-08-18       Impact factor: 91.245

5.  Consulting the community: public expectations and attitudes about genetics research.

Authors:  Holly Etchegary; Jane Green; Elizabeth Dicks; Daryl Pullman; Catherine Street; Patrick Parfrey
Journal:  Eur J Hum Genet       Date:  2013-04-17       Impact factor: 4.246

6.  Increasing participation in genomic research and biobanking through community-based capacity building.

Authors:  Elizabeth Gross Cohn; Maryam Husamudeen; Elaine L Larson; Janet K Williams
Journal:  J Genet Couns       Date:  2014-09-18       Impact factor: 2.537

7.  Translating translational medicine into global health equity: What is needed?

Authors:  Carol Isaacson Barash
Journal:  Appl Transl Genom       Date:  2016-03-10

8.  Proceedings of a Sickle Cell Disease Ontology workshop - Towards the first comprehensive ontology for Sickle Cell Disease.

Authors:  Nicola Mulder; Victoria Nembaware; Adekunle Adekile; Kofi A Anie; Baba Inusa; Biobele Brown; Andrew Campbell; Furahini Chinenere; Catherine Chunda-Liyoka; Vimal K Derebail; Amy Geard; Kais Ghedira; Carol M Hamilton; Neil A Hanchard; Melissa Haendel; Wayne Huggins; Muntaser Ibrahim; Simon Jupp; Karen Kengne Kamga; Jennifer Knight-Madden; Philomène Lopez-Sall; Mamana Mbiyavanga; Deogratias Munube; Damian Nirenberg; Obiageli Nnodu; Solomon Fiifi Ofori-Acquah; Kwaku Ohene-Frempong; Kenneth Babu Opap; Sumir Panji; Miriam Park; Gift Pule; Charmaine Royal; Raphael Sangeda; Bamidele Tayo; Marsha Treadwell; Léon Tshilolo; Ambroise Wonkam
Journal:  Appl Transl Genom       Date:  2016-03-15

9.  Genome science and health disparities: a growing success story?

Authors:  Charles Rotimi; Daniel Shriner; Adebowale Adeyemo
Journal:  Genome Med       Date:  2013-07-29       Impact factor: 11.117

10.  The ethics of sustainable genomic research in Africa.

Authors:  Michael Parker; Dominic P Kwiatkowski
Journal:  Genome Biol       Date:  2016-03-08       Impact factor: 13.583

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  6 in total

1.  Inherited Breast Cancer in Nigerian Women.

Authors:  Yonglan Zheng; Tom Walsh; Suleyman Gulsuner; Silvia Casadei; Ming K Lee; Temidayo O Ogundiran; Adeyinka Ademola; Adeyinka G Falusi; Clement A Adebamowo; Abideen O Oluwasola; Adewumi Adeoye; Abayomi Odetunde; Chinedum P Babalola; Oladosu A Ojengbede; Stella Odedina; Imaria Anetor; Shengfeng Wang; Dezheng Huo; Toshio F Yoshimatsu; Jing Zhang; Gabriela E S Felix; Mary-Claire King; Olufunmilayo I Olopade
Journal:  J Clin Oncol       Date:  2018-08-21       Impact factor: 50.717

Review 2.  Genetics and genomic medicine in Sri Lanka.

Authors:  Nirmala D Sirisena; Vajira H W Dissanayake
Journal:  Mol Genet Genomic Med       Date:  2019-05-20       Impact factor: 2.183

3.  Strategies for Genomic Medicine Education in Low- and Middle-Income Countries.

Authors:  Nirmala D Sirisena; Vajira H W Dissanayake
Journal:  Front Genet       Date:  2019-10-08       Impact factor: 4.599

4.  [Medical genetics services in VenezuelaServiços de genética médica na Venezuela].

Authors:  Carlos A De La Torre-Hernandez; Yvonne Guedez; Lennie Pineda-Bernal; Héctor A Ojeda; Yuliana A Guevara-Guerra
Journal:  Rev Panam Salud Publica       Date:  2018-07-20

5.  Genomics for all in the 21st century?

Authors:  Martina C Cornel; Vence L Bonham
Journal:  J Community Genet       Date:  2017-09-14

6.  Genetic Variants Associated with Clinicopathological Profiles in Sporadic Breast Cancer in Sri Lankan Women.

Authors:  Nirmala Dushyanthi Sirisena; Adebowale Adeyemo; Anchala Ishani Kuruppu; Nilakshi Samaranayake; Vajira Harshadeva Weerabaddana Dissanayake
Journal:  J Breast Cancer       Date:  2018-06-20       Impact factor: 3.588

  6 in total

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