Corrigendum: Adenosine Kinase Inhibition Protects against Cranial Radiation-Induced Cognitive Dysfunction.

[This corrects the article on p. 42 in vol. 9, PMID: 27375429.].

In the original article, in Figure 2 the fourth column (IRR + 5-ITU group) accidentally had incorrect photomicrographs inserted for each channel shown (Merged, ADK, and GFAP). The corrected Figure 2 appears below.

Figure 2

Cranial irradiation elevates adenosine kinase (ADK) immunoreactivity and astrogliosis. Immunofluorescence analysis demonstrates that at 1 month post-treatment, compared to controls (Con and Con + 5-ITU), exposure to cranial irradiation (10 Gy) leads to elevated ADK immunoreactivity (A,B; IRR group; ADK, green; DAPI nuclear counterstain, blue) that is reduced to control levels in irradiated animals treated with 5-ITU (IRR + 5-ITU). Representative confocal micrographs show the presence reactive astrocytic cell bodies (A,C; glial fibrillary acidic protein; GFAP, red) in the hippocampal dentate hilus (DH), sub-granular zone and granule cell layer (GCL) indicating astrogliosis. IRR + 5-ITU animals showed reduced ADK and GFAP immunoreactivity compared to IRR animals. Scale bar: 30 μm.

Similarly, the reference for Osman, A. M. et al. (2014; doi: 10.3727/096368913X674648) has been incorrectly cited. It should be disregarded. The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.