Literature DB >> 28696718

Cross-Metathesis Approach to the Tricyclic Marine Alkaloids (-)-Fasicularin and (-)-Lepadiformine A.

James Burnley1, Zhen J Wang1, W Roy Jackson1, Andrea J Robinson1.   

Abstract

A cross-metathesis protocol has been developed to provide facile access to highly hindered trisubstituted α-branched olefins, which when coupled with a cationic azaspirocyclization reaction, generates the marine alkaloids (-)-fasicularin 2 and a pro-forma synthesis of (-)-lepadiformine A 1.

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Year:  2017        PMID: 28696718     DOI: 10.1021/acs.joc.7b01135

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Bimolecular Cross-Metathesis of a Tetrasubstituted Alkene with Allylic Sulfones.

Authors:  Rishi R Sapkota; Jacqueline M Jarvis; Tanner M Schaub; Marat R Talipov; Jeffrey B Arterburn
Journal:  ChemistryOpen       Date:  2019-02-14       Impact factor: 2.911

2.  Synthesis of 8',11'-dihydrospiro[cyclohexane-1,2'-oxepino[2,3-h] chromen]-4'(3'H)-ones with ring closing metathesis as a key step.

Authors:  Prathima K; Ashok D; Sarasija M; Prabhakar Sripadi; Madhu Vemula; Venkata S Komarraju; Biswajit Gorai; Shyam Prakash
Journal:  RSC Adv       Date:  2018-11-16       Impact factor: 4.036

  2 in total

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