| Literature DB >> 28696240 |
Leighann Sherry1, Ryan Kean1,2, Emily McKloud1, Lindsay E O'Donnell1, Rebecca Metcalfe3, Brian L Jones4, Gordon Ramage5.
Abstract
Vulvovaginal candidiasis (VVC) is a global health problem affecting ∼75% of women at least once in their lifetime. Here we examined the epidemiology of VVC in a patient cohort to identify the causative organisms associated with VVC. Biofilm-forming capacity and antifungal sensitivity profiles were also assessed. We report a shifting prevalence of Candida species with heterogeneous biofilm-forming capacity, which is associated with altered antifungal drug sensitivity.Entities:
Keywords: Candida; biofilm; fluconazole; vulvovaginal candidiasis
Mesh:
Substances:
Year: 2017 PMID: 28696240 PMCID: PMC5571368 DOI: 10.1128/AAC.01065-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191