Wei Xia1,2, Gregor Kasprian3, Daoyu Hu4, Peng Xiao5, Wenzhong Yang6, Xinlin Chen7. 1. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. 176778380@qq.com. 2. Department of Radiology, Hubei Maternal and Children's Hospital, Wuluolu 745, Hongshan District, Wuhan, 430070, China. 176778380@qq.com. 3. Department of Biomedical Imaging and Image-Guided Therapy, Division of Neuroradiology and Musculoskeletal Radiology, Medical University Vienna, A-1090, Vienna, Austria. 4. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. 5. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. 6. Department of Radiology, Hubei Maternal and Children's Hospital, Wuluolu 745, Hongshan District, Wuhan, 430070, China. 7. Department of Ultrasound, Hubei Maternal and Children's Hospital, Wuhan, 430070, China.
Abstract
PURPOSE: The purpose of this study was to evaluate the value of prenatal magnetic resonance imaging (MRI) in characterizing fetal intracranial space occupying lesions in comparison to prenatal ultrasound. METHODS: This retrospective study included 50 fetuses (mean age 26 years, mean gestational weeks 31 + 1 GW) with intracranial space occupying lesions, suspected by prenatal screening ultrasound. T2-weighted, T1-weighted, SSFP, and diffusion-weighted sequences of the fetal brain were obtained on a 1.5 T unit. Pathology (n = 5), postmortem MRI (n = 3), or postnatal US (n = 42) was available as standard of reference. RESULTS: The fetal MRI provided correct diagnosis in 49 cases (98%), while 35 (70%) by ultrasound, and MRI failed in 1 case (2%), while ultrasound failed in 15 cases (30%). Fetal MR and ultrasound were concordant in 35 of 50 cases (70%), completely discordant in 4 (8%), and partially discordant in 11 (22%) cases. CONCLUSIONS: MRI could provide detailed information about the minor lesions, such as focal hemorrhage and periventricular nodules. Meanwhile, it could provide whole view of the lesion in order to delineate the surrounding anatomical structure. But there are still some limitations of its soft-tissue resolution in a case with teratoma; more effort is needed to improve the sequences.
PURPOSE: The purpose of this study was to evaluate the value of prenatal magnetic resonance imaging (MRI) in characterizing fetal intracranial space occupying lesions in comparison to prenatal ultrasound. METHODS: This retrospective study included 50 fetuses (mean age 26 years, mean gestational weeks 31 + 1 GW) with intracranial space occupying lesions, suspected by prenatal screening ultrasound. T2-weighted, T1-weighted, SSFP, and diffusion-weighted sequences of the fetal brain were obtained on a 1.5 T unit. Pathology (n = 5), postmortem MRI (n = 3), or postnatal US (n = 42) was available as standard of reference. RESULTS: The fetal MRI provided correct diagnosis in 49 cases (98%), while 35 (70%) by ultrasound, and MRI failed in 1 case (2%), while ultrasound failed in 15 cases (30%). Fetal MR and ultrasound were concordant in 35 of 50 cases (70%), completely discordant in 4 (8%), and partially discordant in 11 (22%) cases. CONCLUSIONS: MRI could provide detailed information about the minor lesions, such as focal hemorrhage and periventricular nodules. Meanwhile, it could provide whole view of the lesion in order to delineate the surrounding anatomical structure. But there are still some limitations of its soft-tissue resolution in a case with teratoma; more effort is needed to improve the sequences.
Entities:
Keywords:
Fetus; Intracranial; MRI; Prenatal diagnosis; Space occupying lesion
Authors: L Breysem; H Bosmans; S Dymarkowski; D Van Schoubroeck; I Witters; J Deprest; P Demaerel; D Vanbeckevoort; C Vanhole; P Casaer; M Smet Journal: Eur Radiol Date: 2003-04-15 Impact factor: 5.315
Authors: Barbara Ulm; Dana Muin; Anke Scharrer; Daniela Prayer; Gregor Dovjak; Gregor Kasprian Journal: Acta Obstet Gynecol Scand Date: 2020-06-26 Impact factor: 4.544