Literature DB >> 28694860

Postpartum Aortic Bifurcation Thrombosis on the Background of Thrombophilic Disorder.

Roxana Elena Bohîltea1, Natalia Turcan2, Horia Muresian1, Silvia Condu2, Elvira Bratila1, Monica Mihaela Cîrstoiu1.   

Abstract

Two main causes of arterial thrombosis are known: fi rst - atherosclerosis, extensively studied, and the second - atrial fi brillation. The lack of any risk factors and the occurrence at young age of a thrombotic event requires us to investigate possible other conditions, including inherited thrombophilia that is represented by a series of genetic disorders that increase the risk of thromboembolic disease. The role of thrombophilia in the occurrence of arterial thrombosis is inconsequential; this disorder is characterized by the tendency of developing venous thrombosis. We present a rare case of a 29 year old woman that presents an arterial thrombotic event subsequent to the caesarean section. The patient had a positive familial history for thrombotic events and a cavernous sinus thrombosis in personal history. Prophylactic treatment with unfractionated heparin throughout pregnancy was applied. At 31 weeks gestation the patient underwent cesarean surgery for nonreassuring fetal status, 2 weeks fetal intrauterine growth restriction and absent diastolic fl ow of uterine arteries. Three days post operatory arterial thrombosis is suspected. The context that led to this suspicion was paresthesia, color modifi cation of the right leg and abolished popliteal pulse. Angiographic-CT confi rmed the presumptive diagnosis. A cardiovascular, conservatory treatment was successfully applied. Considering the particularities of the presented case we discuss the occurrence of arterial thrombosis postpartum in the context of confi rmed thrombophilia by reviewing the specialized literature.

Entities:  

Year:  2016        PMID: 28694860      PMCID: PMC5486167     

Source DB:  PubMed          Journal:  Maedica (Bucur)        ISSN: 1841-9038


  9 in total

Review 1.  The association between hereditary thrombophilias and pregnancy loss.

Authors:  Géraldine Lissalde-Lavigne; Eva Cochery-Nouvellon; Eric Mercier; Isabelle Quéré; Michel Dauzat; Pierre Marès; Jean-Christophe Gris
Journal:  Haematologica       Date:  2005-09       Impact factor: 9.941

2.  Genetic thrombophilic mutations among couples with recurrent miscarriage.

Authors:  S Jivraj; R Rai; J Underwood; L Regan
Journal:  Hum Reprod       Date:  2006-01-23       Impact factor: 6.918

3.  Prenatal renal vein thrombosis in dichorionic twin pregnancy.

Authors:  Sarah K Weber; Andreas Müller; Annegret Geipel; Christoph Berg; Ulrich Gembruch
Journal:  Arch Gynecol Obstet       Date:  2014-04-23       Impact factor: 2.344

4.  Frequency of thrombophilia in patients with adverse pregnancy outcome.

Authors:  Nazli Hossain; Tahir Shamsi; Nargis Soomro
Journal:  J Pak Med Assoc       Date:  2005-06       Impact factor: 0.781

5.  Inherited thrombophilia and first venous thromboembolism during pregnancy and puerperium.

Authors:  Ida Martinelli; Valerio De Stefano; Emanuela Taioli; Katia Paciaroni; Elena Rossi; Pier Mannuccio Mannucci
Journal:  Thromb Haemost       Date:  2002-05       Impact factor: 5.249

6.  Thrombophilia is significantly associated with severe preeclampsia: results of a large-scale, case-controlled study.

Authors:  Giorgio Mello; Elena Parretti; Luca Marozio; Cristina Pizzi; Andrea Lojacono; Tiziana Frusca; Fabio Facchinetti; Chiara Benedetto
Journal:  Hypertension       Date:  2005-10-24       Impact factor: 10.190

Review 7.  Thrombosis in pregnancy and maternal outcomes.

Authors:  Andra H James
Journal:  Birth Defects Res C Embryo Today       Date:  2015-09-18

Review 8.  Thrombophilia in pregnancy: a systematic review.

Authors:  L Robertson; O Wu; P Langhorne; S Twaddle; P Clark; G D O Lowe; I D Walker; M Greaves; I Brenkel; L Regan; I A Greer
Journal:  Br J Haematol       Date:  2006-01       Impact factor: 6.998

Review 9.  Risk factors for thrombosis in pregnancy.

Authors:  William M Hague; Gustaaf A Dekker
Journal:  Best Pract Res Clin Haematol       Date:  2003-06       Impact factor: 3.020

  9 in total

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