Literature DB >> 2869262

Isolation of AIDS-associated retrovirus from genital secretions of women with antibodies to the virus.

C B Wofsy, J B Cohen, L B Hauer, N S Padian, B A Michaelis, L A Evans, J A Levy.   

Abstract

The AIDS-associated retrovirus (ARV) was isolated from vaginal and/or cervical secretions from 4 out of 8 women whose sera contained antibodies to the virus. The quantity of virus recovered initially was so low that identification of ARV was accomplished only after passage of the isolates to cultured mitogen-stimulated normal human peripheral blood mononuclear cells. The results indicate that the vaginal canal under certain conditions could be a source of transmission of ARV.

Entities:  

Keywords:  Acquired Immunodeficiency Syndrome; Americas; Biology; Cervical Mucus--analysis; Cervix; Developed Countries; Developing Countries; Diseases; Genitalia; Genitalia, Female; Hiv Infections; North America; Northern America; Physiology; United States; Urogenital System; Uterus; Vagina; Viral Diseases

Mesh:

Substances:

Year:  1986        PMID: 2869262     DOI: 10.1016/s0140-6736(86)90885-8

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


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