| Literature DB >> 28692103 |
Yang Cao1, Dong Liu, Wen-Bin Zhang.
Abstract
We report a supercharged, intrinsically disordered protein, SpyCatcher(-), possessing stimuli-responsive reactivity toward SpyTag with tunable yields ranging from 4% to 98% depending on pH, temperature, ionic strength, etc. The CD and NMR studies reveal that the reaction occurs through a folded intermediate formed probably via a different mechanism from that of SpyCatcher.Entities:
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Year: 2017 PMID： 28692103 DOI： 10.1039/c7cc04507g
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222