Literature DB >> 28691675

Incidental thyroid carcinomas. A retrospective study.

A Maturo, L Tromba, L De Anna, G Carbotta, G Livadoti, C Donello, F Falbo, G Galiffa, Antonella Esposito, A Biancucci, S Carbotta.   

Abstract

AIM: The aim of the present study is to report our series of incidental thyroid carcinomas in the last 15 years and their follow-up, discussing therapeutics indications and surgical choices. PATIENTS AND METHODS: We have considered 1793 patients operated on Surgical Sciences Department of "Sapienza" University of Rome from January 1, 2001 to December 31, 2015. The study was conducted on 83 totally thyroidectomized patients with a real incidental thyroid carcinoma, by clinical, laboratory and instrumental controls. Whole-body scan was the most important test in postoperative evaluation.
RESULTS: In our series, the incidence of incidental carcinomas was 4.62%. Compared to the total number of cancer patients, the percentage is 21,9%. In 15.66% of cases there was multifocality and in 7.23% also bilaterality. Regarding the histological type, in all cases they were papillary carcinoma. The size of the neoplastic lesions ranged from a minimum of 3 to a maximum of 10 mm. Whole-body scan revealed lymph node metastasis in 57.69% of patients. DISCUSSION: Comparing these data with our previous studies we have seen a significant increase in incidence of incidental thyroid carcinomas over the years. Our therapeutical choice is total thyroidectomy and complection thyroidectomy after lobectomy, because of a relevant percentage of multifocality and/or bilaterality of these tumors. Many Authors on the contrary prefer a more conservative approach invoking the good prognosis of these tumors. The 57.69% of lymph node metastasis at postoperative whole-body scan comfort us in our setting.
CONCLUSION: Incidental thyroid carcinomas are not uncommon. We consider only tumors until 1 cm in diameter. Multifocality and bilaterality are often present such as occult lymph node metastasis. Our therapeutical choice is total thyroidectomy in order to conduct a proper follow-up.

Entities:  

Mesh:

Year:  2017        PMID: 28691675      PMCID: PMC5509392          DOI: 10.11138/gchir/2017.38.2.094

Source DB:  PubMed          Journal:  G Chir        ISSN: 0391-9005


  105 in total

1.  Cancer recurrence in papillary thyroid microcarcinoma: a multivariate analysis on 231 patients with a 12-year follow-up.

Authors:  L Pedrazzini; A Baroli; L Marzoli; R Guglielmi; E Papini
Journal:  Minerva Endocrinol       Date:  2013-09       Impact factor: 2.184

2.  Selective inhibitors of aurora kinases inhibit proliferation, reduce cell viability and impair cell cycle progression in papillary thyroid carcinoma cells.

Authors:  E Baldini; C Tuccilli; N Prinzi; S Sorrenti; A Antonelli; P Fallahi; C Mian; S Barollo; A Catania; S Morrone; F Tartaglia; D Mascagni; C Coccaro; M Pepe; A Filippini; M D'Armiento; S Ulisse
Journal:  J Biol Regul Homeost Agents       Date:  2015 Oct-Dec       Impact factor: 1.711

3.  Occult papillary carcinoma of the thyroid. A "normal" finding in Finland. A systematic autopsy study.

Authors:  H R Harach; K O Franssila; V M Wasenius
Journal:  Cancer       Date:  1985-08-01       Impact factor: 6.860

4.  Expression and prognostic value of the cell polarity PAR complex members in thyroid cancer.

Authors:  Chiara Tuccilli; Enke Baldini; Yannick Arlot-Bonnemains; Frank Chesnel; Salvatore Sorrenti; Corrado De Vito; Eleonora D'Armiento; Alessandro Antonelli; Poupak Fallahi; Sara Watutantrige; Francesco Tartaglia; Susi Barollo; Caterina Mian; Stefano Arcieri; Domenico Mascagni; Daniele Pironi; Marco Bononi; Massimo Vergine; Massimo Monti; Angelo Filippini; Salvatore Ulisse
Journal:  Int J Oncol       Date:  2017-03-08       Impact factor: 5.650

5.  Early discharge after total thyroidectomy: a retrospective feasibility study.

Authors:  F Tartaglia; A Giuliani; S Sorrenti; L Tromba; S Carbotta; A Maturo; G Carbotta; L De Anna; R Merola; G Livadoti; F Pelle; S Ulisse
Journal:  G Chir       Date:  2016 Nov-Dec

6.  Ultrasonography-guided fine-needle aspiration of thyroid incidentaloma: correlation with pathological findings.

Authors:  Il Seong Nam-Goong; Ha Young Kim; Gyungyub Gong; Ho Kyu Lee; Suck Joon Hong; Won Bae Kim; Young Kee Shong
Journal:  Clin Endocrinol (Oxf)       Date:  2004-01       Impact factor: 3.478

7.  Incidental cancer in multinodular goitre post thyroidectomy.

Authors:  I Bombil; A Bentley; D Kruger; T E Luvhengo
Journal:  S Afr J Surg       Date:  2014-02       Impact factor: 0.375

8.  Prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: a blinded sonographic evaluation.

Authors:  L Tromba; S Blasi; A Vestri; D Kiltzanidi; F Tartaglia; A Redler
Journal:  Phlebology       Date:  2013-11-15       Impact factor: 1.740

9.  Ultrasound-guided percutaneous laser ablation of papillary thyroid microcarcinoma: a feasibility study on three cases with pathological and immunohistochemical evaluation.

Authors:  Roberto Valcavi; Simonetta Piana; Giorgio Stecconi Bortolan; Roberta Lai; Verter Barbieri; Roberto Negro
Journal:  Thyroid       Date:  2013-11-14       Impact factor: 6.568

10.  An Incidental Primary Papillary Carcinoma Arising in a Thyroglossal Duct Cyst: Report of a Rare Finding.

Authors:  Mohammad Jaseem Hassan; Safia Rana; Sabina Khan; Zeeba Shamim Jairajpuri; Seema Monga; Abhinav Jain; Sujata Jetley
Journal:  J Lab Physicians       Date:  2016 Jan-Jun
View more
  4 in total

1.  Rare Occurrence of Incidental Finding of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features in Hürthle Cell Adenoma.

Authors:  Biserka Pigac; Silvija Masic; Zdenka Hutinec; Valentina Masic
Journal:  Med Arch       Date:  2018-11

2.  Clinical-pathological issues in thyroid pathology: study on the routine application of NIFTP diagnostic criteria.

Authors:  Valentina Canini; Davide Leni; Angela Ida Pincelli; Marcella Scardilli; Mattia Garancini; Chiara Villa; Camillo Di Bella; Giulia Capitoli; Riccardo Cimini; Biagio Eugenio Leone; Fabio Pagni
Journal:  Sci Rep       Date:  2019-09-12       Impact factor: 4.379

3.  Incidental thyroid carcinoma: Correlation between FNAB cytology and pathological examination in 1093 cases.

Authors:  Mariana Gonçalves Rodrigues; Luiz Fernando Ferraz da Silva; Vergilius José Furtado de Araujo-Filho; Letícia de Moraes Mosca; Vergilius José Furtado de Araujo-Neto; Luiz Paulo Kowalski; Paulo Campos Carneiro
Journal:  Clinics (Sao Paulo)       Date:  2022-03-17       Impact factor: 2.365

4.  Klotho Inhibits Proliferation in a RET Fusion Model of Papillary Thyroid Cancer by Regulating the Wnt/β-Catenin Pathway.

Authors:  Qiong Wu; Liang Jiang; Jiang Wu; HaiFang Dong; Yaping Zhao
Journal:  Cancer Manag Res       Date:  2021-06-17       Impact factor: 3.989

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.