Literature DB >> 28691193

Fluralaner as a single dose oral treatment for Caparinia tripilis in a pygmy African hedgehog.

Camilo Romero1, Galia Sheinberg Waisburd2, Jocelyn Pineda1, Rafael Heredia1, Enrique Yarto2, Alberto M Cordero3.   

Abstract

BACKGROUND: African pygmy hedgehogs (Atelerix albiventris) are popular pets belonging to the Erinaceidae family of spined mammals. Amongst the most common skin diseases occurring in this species is infestation caused by the mite Caparinia spp. Due to their skin anatomy and spiny coat, detection of skin lesions in these hedgehogs can be difficult. This may result in delays in seeking medical care, which may lead to secondary bacterial infection and self-inflicted trauma. Multiple therapies have been used in the treatment of this skin condition including ivermectin, amitraz, fipronil and selamectin. A drug which could be administered as a single oral dose would be advantageous to these pets and their owners.
OBJECTIVE: To evaluate the effect of a single oral dose (15 mg/kg) of fluralaner on Caparinia tripilis infestation in the African pygmy hedgehog. ANIMALS: A 10-month-old African pygmy hedgehog weighing 184 g.
METHODS: Response to treatment was monitored by dermatological examination and superficial skin scrapings repeated at 7, 14, 21, 30, 60, 90 and 120 days following fluralaner administration.
RESULTS: On Day 7 after treatment, adult mites were observed exhibiting normal movement. On Day 14, only dead mites were observed. No life stages of the mites were found after Day 21. CONCLUSION AND CLINICAL IMPORTANCE: A single oral dose at 15 mg/kg of fluralaner was effective within 21 days after treatment for capariniasis in this case. Further studies are required to evaluate the drug's safety and toxicology in hedgehogs, and to confirm efficacy.
© 2017 ESVD and ACVD.

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Year:  2017        PMID: 28691193     DOI: 10.1111/vde.12465

Source DB:  PubMed          Journal:  Vet Dermatol        ISSN: 0959-4493            Impact factor:   1.589


  2 in total

1.  Oral fluralaner as a treatment for Demodex aurati and Demodex criceti in a golden (Syrian) hamster (Mesocricetus auratus).

Authors:  Gabrielle Brosseau
Journal:  Can Vet J       Date:  2020-02       Impact factor: 1.008

Review 2.  A rapid evidence assessment of the potential risk to the environment presented by active ingredients in the UK's most commonly sold companion animal parasiticides.

Authors:  Clodagh Wells; C M Tilly Collins
Journal:  Environ Sci Pollut Res Int       Date:  2022-04-24       Impact factor: 5.190

  2 in total

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