Literature DB >> 28690323

Mechanisms of sterile inflammation in acetaminophen hepatotoxicity.

Hartmut Jaeschke1.   

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Year:  2017        PMID： 28690323      PMCID： PMC5827177          DOI： 10.1038/cmi.2017.49

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


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  10 in total

1.  Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.

Authors:  Chao Zhang; Jin Feng; Jun Du; Zhiyong Zhuo; Shuo Yang; Weihong Zhang; Weihong Wang; Shengyuan Zhang; Yoichiro Iwakura; Guangxun Meng; Yang-Xin Fu; Baidong Hou; Hong Tang
Journal:  Cell Mol Immunol       Date:  2017-05-15       Impact factor: 11.530

2.  Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.

Authors:  C David Williams; Mary Lynn Bajt; Matthew R Sharpe; Mitchell R McGill; Anwar Farhood; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2014-01-15       Impact factor: 4.219

Review 3.  Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity.

Authors:  Hartmut Jaeschke; C David Williams; Anup Ramachandran; Mary L Bajt
Journal:  Liver Int       Date:  2011-03-14       Impact factor: 5.828

Review 4.  Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity.

Authors:  Hartmut Jaeschke; Mitchell R McGill; Anup Ramachandran
Journal:  Drug Metab Rev       Date:  2012-01-10       Impact factor: 4.518

Review 5.  Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure.

Authors:  Benjamin L Woolbright; Hartmut Jaeschke
Journal:  J Hepatol       Date:  2016-11-29       Impact factor: 25.083

6.  Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury.

Authors:  C David Williams; Daniel J Antoine; Patrick J Shaw; Craig Benson; Anwar Farhood; Dominic P Williams; Thirumala-Devi Kanneganti; B Kevin Park; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2011-03-21       Impact factor: 4.219

7.  Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury.

Authors:  C David Williams; Anwar Farhood; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2010-07-15       Impact factor: 4.219

8.  Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans.

Authors:  Charalambos Gustav Antoniades; Alberto Quaglia; Leonie S Taams; Ragai R Mitry; Munther Hussain; Robin Abeles; Lucia A Possamai; Matthew Bruce; Mark McPhail; Christopher Starling; Bart Wagner; Adrian Barnardo; Sabine Pomplun; Georg Auzinger; William Bernal; Nigel Heaton; Diego Vergani; Mark R Thursz; Julia Wendon
Journal:  Hepatology       Date:  2012-07-06       Impact factor: 17.425

9.  Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

Authors:  Avlin B Imaeda; Azuma Watanabe; Muhammad A Sohail; Shamail Mahmood; Mehdi Mohamadnejad; Fayyaz S Sutterwala; Richard A Flavell; Wajahat Z Mehal
Journal:  J Clin Invest       Date:  2009-01-26       Impact factor: 14.808

Review 10.  Acetaminophen-induced Liver Injury: from Animal Models to Humans.

Authors:  Hartmut Jaeschke; Yuchao Xie; Mitchell R McGill
Journal:  J Clin Transl Hepatol       Date:  2014-09-15
  10 in total
  2 in total

1.  Hyperglycemia exacerbates acetaminophen-induced acute liver injury by promoting liver-resident macrophage proinflammatory response via AMPK/PI3K/AKT-mediated oxidative stress.

Authors:  Qi Wang; Song Wei; Haoming Zhou; Gefenqiang Shen; Xiaojie Gan; Shun Zhou; Jiannan Qiu; Chenyu Shi; Ling Lu
Journal:  Cell Death Discov       Date:  2019-07-19

2.  Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways.

Authors:  Mahmoud Elshal; Marwa E Abdelmageed
Journal:  Arch Pharm Res       Date:  2022-03-04       Impact factor: 4.946
  2 in total

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