| Literature DB >> 28689567 |
Bertrand Fougère1, Julien Delrieu2, Natalia Del Campo3, Gaëlle Soriano2, Sandrine Sourdet1, Bruno Vellas1.
Abstract
Physical frailty is often associated with cognitive impairment, possibly because of common underlying pathophysiologic mechanisms. To stimulate research in this field, the concept cognitive frailty was proposed, emphasizing the important role of brain aging. Cognitive frailty was defined as the presence of cognitive deficits in physically frail older persons without dementia. This subtype of frailty is deemed important, as it may represent a prodromal phase for neurodegenerative diseases and is potentially a suitable target for early intervention. The aim of this report is to refine the framework for the definition and mechanisms of cognitive frailty and relevant screening tools.Entities:
Keywords: Cognition; Cognitive frailty; Frailty; Mechanisms; Prevention
Mesh:
Year: 2017 PMID: 28689567 DOI: 10.1016/j.cger.2017.03.001
Source DB: PubMed Journal: Clin Geriatr Med ISSN: 0749-0690 Impact factor: 3.076