Literature DB >> 28689491

Deceptive nasal NK/T-cell lymphoma.

Jagdeep S Thakur1, Aditi Mahajan2, Manika Saluja2, Narinder K Mohindroo3.   

Abstract

Nasal NK/T cell lymphoma is rare and it easily masquerades as chronic rhinosinusitis. It has a very poor prognosis and hence early diagnosis, although difficult, is necessary for better outcome. We present a case of a 30-year-old man who presented with nasal obstruction, facial oedema and crusts. High-resolution computed tomography found soft tissue in all sinuses and the nasal cavity. Endoscopic biopsy revealed necrotic and inflammatory tissue with fungi on culture. A diagnosis of fungal rhinosinusitis was made but the patient did not respond to antifungal drugs. A histopathology review with immunohistochemistry suggested nasal NK/T cell lymphoma. The patient was started on chemotherapy but died within 1 week.

Entities:  

Keywords:  Diagnosis; Extranodal NK-T-cell Lymphoma; Fungal pathology; Lethal midline granuloma; Nose; Sinusitis

Mesh:

Year:  2016        PMID: 28689491     DOI: 10.1177/0049475516684088

Source DB:  PubMed          Journal:  Trop Doct        ISSN: 0049-4755            Impact factor:   0.731


  3 in total

1.  Lethal Midline Granuloma: An Enigma in Diagnosis-A Rare Case Report.

Authors:  K C Prasad; N Harshitha; T R Harshita; D Aishwarya Raj Pillai; H S Brindha
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2019-03-15

2.  Rhino-Orbital-Cerebral Mycosis and Extranodal Natural Killer or/and T-Cell Lymphoma, Nasal Type.

Authors:  Dong Ming Li; Li De Lun
Journal:  Front Med (Lausanne)       Date:  2022-06-17

3.  Case Report: Rhizopus arrhizus Rhino-Orbital-Cerebral Mycosis and Lethal Midline Granuloma: Another Fungal Etiological Agent.

Authors:  Dong Ming Li; Li De Lun; Jie Ge; Gong Jie Zhang; Xin Lun Li; G Sybren de Hoog
Journal:  Front Med (Lausanne)       Date:  2021-06-02
  3 in total

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